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    LTBP1 latent transforming growth factor beta binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 4052, updated on 3-Nov-2024

    Summary

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    Official Symbol
    LTBP1provided by HGNC
    Official Full Name
    latent transforming growth factor beta binding protein 1provided by HGNC
    Primary source
    HGNC:HGNC:6714
    See related
    Ensembl:ENSG00000049323 MIM:150390; AllianceGenome:HGNC:6714
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ARCL2E
    Summary
    The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
    Expression
    Broad expression in gall bladder (RPKM 40.6), placenta (RPKM 32.5) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See LTBP1 in Genome Data Viewer
    Location:
    2p22.3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (32946953..33399509)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (32992680..33445650)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (33172020..33624576)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr2:33111152-33111352 Neighboring gene uncharacterized LOC105374453 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_58246 Neighboring gene uncharacterized LOC100271832 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11344 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11345 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11346 Neighboring gene Sharpr-MPRA regulatory region 2981 Neighboring gene NANOG hESC enhancer GRCh37_chr2:33281163-33281664 Neighboring gene Sharpr-MPRA regulatory region 6273 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:33294707-33295906 Neighboring gene H2AC histone family pseudogene 2 Neighboring gene tRNA-yW synthesizing protein 1 homolog pseudogene 1 Neighboring gene NANOG hESC enhancer GRCh37_chr2:33444164-33444665 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:33534151-33534349 Neighboring gene RNA, 5S ribosomal pseudogene 91 Neighboring gene RNA, 5S ribosomal pseudogene 92 Neighboring gene microRNA 4430 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15562 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15563 Neighboring gene RAS guanyl releasing protein 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11347 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15564 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15565 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15566 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15567 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15568 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15569 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11348 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11349 Neighboring gene RASGRP3 antisense RNA 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. The alteration of plasma TGF-β1 levels in patients with brain tumors after tumor removal. Loh JK, et al. Kaohsiung J Med Sci, 2012 Jun. PMID 22632886
    2. LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation. Cai R, et al. J Transl Med, 2020 Mar 26. PMID 32216815, Free PMC Article
    3. Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF beta. Massam-Wu T, et al. J Cell Sci, 2010 Sep 1. PMID 20699357, Free PMC Article
    4. PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia. Zhao Q, et al. Mol Cell, 2020 Jan 2. PMID 31628042
    5. Localization of latent transforming growth factor-β binding protein-1 in human coronary atherosclerotic plaques. Oklü R, et al. Circ J, 2011. PMID 21071877

    See all (143) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A prognostic marker LTBP1 is associated with epithelial mesenchymal transition and can promote the progression of gastric cancer.
      Title: A prognostic marker LTBP1 is associated with epithelial mesenchymal transition and can promote the progression of gastric cancer.
    2. Targeted Mass Spectrometry of Longitudinal Patient Sera Reveals LTBP1 as a Potential Surveillance Biomarker for High-Grade Serous Ovarian Carcinoma.
      Title: Targeted Mass Spectrometry of Longitudinal Patient Sera Reveals LTBP1 as a Potential Surveillance Biomarker for High-Grade Serous Ovarian Carcinoma.
    3. Immune suppressive signaling regulated by latent transforming growth factor beta binding protein 1 promotes metastasis in cervical cancer.
      Title: Immune suppressive signaling regulated by latent transforming growth factor beta binding protein 1 promotes metastasis in cervical cancer.
    4. LTBP1 promotes fibrillin incorporation into the extracellular matrix.
      Title: LTBP1 promotes fibrillin incorporation into the extracellular matrix.
    5. POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.
      Title: POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.
    6. LTBP1 plays a potential bridge between depressive disorder and glioblastoma.
      Title: LTBP1 plays a potential bridge between depressive disorder and glioblastoma.
    7. Bi-allelic premature truncating variants in LTBP1 cause cutis laxa syndrome.
      Title: Bi-allelic premature truncating variants in LTBP1 cause cutis laxa syndrome.
    8. LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.
      Title: LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.
    9. Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis.
      Title: Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.
    10. MiR-27a-5p was expressed 11 times higher in OD-Exo, while miR-27a-5p promoted odontogenic differentiation of DPSCs and significantly upregulated TGFbeta1, TGFR1, p-Smad2/3, and Smad4 by downregulating the inhibitory molecule LTBP1.
      Title: Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAs.
    Submit: New GeneRIF Correction See all GeneRIFs (72)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Cutis laxa, autosomal recessive, type 2E
    MedGen: C5561944 OMIM: 619451 GeneReviews: Not available
    		not available

    EBI GWAS Catalog

    Description
    A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
    EBI GWAS Catalog
    Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
    EBI GWAS Catalog
    Hundreds of variants clustered in genomic loci and biological pathways affect human height.
    EBI GWAS Catalog
    Identification of 15 loci influencing height in a Korean population.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC163161

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables extracellular matrix structural constituent RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables microfibril binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microfibril binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables molecular adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables receptor ligand inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transforming growth factor beta binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transforming growth factor beta receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein serine/threonine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in establishment of protein localization to extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sequestering of TGFbeta in extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sequestering of TGFbeta in extracellular matrix TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with collagen-containing extracellular matrix HDA PubMed 
    located_in collagen-containing extracellular matrix HDA PubMed 
    located_in collagen-containing extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum lumen TAS
    Traceable Author Statement
    more info
    		  
    located_in extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular matrix NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in extracellular region HDA PubMed 
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    		  
    located_in microfibril IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    latent-transforming growth factor beta-binding protein 1
    Names
    LTBP-1
    TGF-beta1-BP-1
    transforming growth factor beta-1-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_000627.4 → NP_000618.4  latent-transforming growth factor beta-binding protein 1 isoform LTBP-1S precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (LTBP-1S) contains a shorter and distinct N-terminus, compared to isoform LTBP-1L.
      Source sequence(s)
      AC019127, AC019195, AC020594
      Consensus CDS
      CCDS33178.2
      UniProtKB/TrEMBL
      B7ZLY3
      Related
      ENSP00000384091.1, ENST00000407925.5
      Conserved Domains (6) summary
      smart00179
      Location:876 → 917
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:672 → 705
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:589 → 629
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:363 → 404
      TB; TB domain
      pfam12662
      Location:570 → 592
      cEGF; Complement Clr-like EGF-like

    2. NM_001166264.2 → NP_001159736.2  latent-transforming growth factor beta-binding protein 1 isoform 4 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform LTBP-1L.
      Source sequence(s)
      AC019127, AC019195, AC020594
      Consensus CDS
      CCDS54344.1
      UniProtKB/TrEMBL
      B7ZLY3, E7EV71
      Related
      ENSP00000393057.2, ENST00000418533.6
      Conserved Domains (6) summary
      smart00179
      Location:876 → 917
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:672 → 705
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:589 → 629
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:363 → 404
      TB; TB domain
      pfam12662
      Location:570 → 592
      cEGF; Complement Clr-like EGF-like

    3. NM_001166265.2 → NP_001159737.2  latent-transforming growth factor beta-binding protein 1 isoform 3 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform LTBP-1L.
      Source sequence(s)
      AC019127, AC019195, AC020594
      Consensus CDS
      CCDS54345.1
      UniProtKB/TrEMBL
      C9JD84
      Related
      ENSP00000385359.1, ENST00000404525.5
      Conserved Domains (5) summary
      smart00179
      Location:823 → 864
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:619 → 652
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:536 → 576
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:980 → 1023
      TB; TB domain
      pfam12662
      Location:517 → 539
      cEGF; Complement Clr-like EGF-like

    4. NM_001166266.2 → NP_001159738.2  latent-transforming growth factor beta-binding protein 1 isoform 5 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region, and uses an alternate in-frame splice site and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (5) has a distinct N-terminus and is shorter than isoform LTBP-1L.
      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (5) summary
      smart00179
      Location:823 → 864
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:619 → 652
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:536 → 576
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:938 → 981
      TB; TB domain
      pfam12662
      Location:517 → 539
      cEGF; Complement Clr-like EGF-like

    5. NM_001394905.1 → NP_001381834.1  latent-transforming growth factor beta-binding protein 1 isoform 6 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594, AL133244
      Conserved Domains (5) summary
      smart00179
      Location:1149 → 1190
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:945 → 978
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:862 → 902
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:1306 → 1349
      TB; TB domain
      pfam12662
      Location:843 → 865
      cEGF; Complement Clr-like EGF-like

    6. NM_001394906.1 → NP_001381835.1  latent-transforming growth factor beta-binding protein 1 isoform 7 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (3) summary
      smart00179
      Location:875 → 916
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:671 → 704
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:588 → 628
      EGF_CA; Calcium-binding EGF domain

    7. NM_001394907.1 → NP_001381836.1  latent-transforming growth factor beta-binding protein 1 isoform 8 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:847 → 888
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:643 → 676
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:560 → 600
      EGF_CA; Calcium-binding EGF domain

    8. NM_001394908.1 → NP_001381837.1  latent-transforming growth factor beta-binding protein 1 isoform 9 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (3) summary
      smart00179
      Location:836 → 877
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      pfam07645
      Location:589 → 629
      EGF_CA; Calcium-binding EGF domain

    9. NM_001394909.1 → NP_001381838.1  latent-transforming growth factor beta-binding protein 1 isoform 10 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (4) summary
      smart00179
      Location:834 → 875
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:630 → 663
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:547 → 587
      EGF_CA; Calcium-binding EGF domain

    10. NM_001394910.1 → NP_001381839.1  latent-transforming growth factor beta-binding protein 1 isoform 11 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (3) summary
      smart00179
      Location:875 → 916
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:671 → 704
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:588 → 628
      EGF_CA; Calcium-binding EGF domain

    11. NM_001394911.1 → NP_001381840.1  latent-transforming growth factor beta-binding protein 1 isoform 12 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (3) summary
      smart00179
      Location:833 → 874
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:629 → 662
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:546 → 586
      EGF_CA; Calcium-binding EGF domain

    12. NM_001394912.1 → NP_001381841.1  latent-transforming growth factor beta-binding protein 1 isoform 13 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (4) summary
      smart00179
      Location:876 → 917
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:672 → 705
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:589 → 629
      EGF_CA; Calcium-binding EGF domain

    13. NM_001394913.1 → NP_001381842.1  latent-transforming growth factor beta-binding protein 1 isoform 14 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:822 → 863
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:618 → 651
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:535 → 575
      EGF_CA; Calcium-binding EGF domain

    14. NM_001394914.1 → NP_001381843.1  latent-transforming growth factor beta-binding protein 1 isoform 15 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (4) summary
      smart00179
      Location:806 → 847
      EGF_CA; Calcium-binding EGF-like domain
      PRK03427
      Location:397 → 511
      PRK03427; cell division protein ZipA; Provisional
      cd00054
      Location:602 → 635
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:519 → 559
      EGF_CA; Calcium-binding EGF domain

    15. NM_001394915.1 → NP_001381844.1  latent-transforming growth factor beta-binding protein 1 isoform 16 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (4) summary
      smart00179
      Location:848 → 889
      EGF_CA; Calcium-binding EGF-like domain
      PRK03427
      Location:397 → 511
      PRK03427; cell division protein ZipA; Provisional
      cd00054
      Location:644 → 677
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:561 → 601
      EGF_CA; Calcium-binding EGF domain

    16. NM_001394916.1 → NP_001381845.1  latent-transforming growth factor beta-binding protein 1 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (4) summary
      smart00179
      Location:795 → 836
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:335 → 461
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:591 → 624
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:508 → 548
      EGF_CA; Calcium-binding EGF domain

    17. NM_001394917.1 → NP_001381846.1  latent-transforming growth factor beta-binding protein 1 isoform 18 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (5) summary
      smart00179
      Location:834 → 875
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:630 → 663
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:547 → 587
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:363 → 404
      TB; TB domain

    18. NM_001394918.1 → NP_001381847.1  latent-transforming growth factor beta-binding protein 1 isoform 19 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (4) summary
      smart00179
      Location:876 → 917
      EGF_CA; Calcium-binding EGF-like domain
      PHA03247
      Location:416 → 542
      PHA03247; large tegument protein UL36; Provisional
      cd00054
      Location:672 → 705
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:589 → 629
      EGF_CA; Calcium-binding EGF domain

    19. NM_001394919.1 → NP_001381848.1  latent-transforming growth factor beta-binding protein 1 isoform 20 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      B7ZLY3
      Conserved Domains (3) summary
      smart00179
      Location:875 → 916
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:671 → 704
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:588 → 628
      EGF_CA; Calcium-binding EGF domain

    20. NM_001394920.1 → NP_001381849.1  latent-transforming growth factor beta-binding protein 1 isoform 21 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:781 → 822
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:577 → 610
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:494 → 534
      EGF_CA; Calcium-binding EGF domain

    21. NM_001394921.1 → NP_001381850.1  latent-transforming growth factor beta-binding protein 1 isoform 22 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:822 → 863
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:618 → 651
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:535 → 575
      EGF_CA; Calcium-binding EGF domain

    22. NM_001394923.1 → NP_001381852.1  latent-transforming growth factor beta-binding protein 1 isoform 23 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (2) summary
      smart00179
      Location:741 → 782
      EGF_CA; Calcium-binding EGF-like domain
      pfam07645
      Location:494 → 534
      EGF_CA; Calcium-binding EGF domain

    23. NM_001394924.1 → NP_001381853.1  latent-transforming growth factor beta-binding protein 1 isoform 24 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:781 → 822
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:577 → 610
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:494 → 534
      EGF_CA; Calcium-binding EGF domain

    24. NM_001394925.1 → NP_001381854.1  latent-transforming growth factor beta-binding protein 1 isoform 25 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:823 → 864
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:619 → 652
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:536 → 576
      EGF_CA; Calcium-binding EGF domain

    25. NM_001394926.1 → NP_001381855.1  latent-transforming growth factor beta-binding protein 1 isoform 26 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:781 → 822
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:577 → 610
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:494 → 534
      EGF_CA; Calcium-binding EGF domain

    26. NM_001394927.1 → NP_001381856.1  latent-transforming growth factor beta-binding protein 1 isoform 27 precursor

      Status: REVIEWED

      Source sequence(s)
      AC019127, AC019195, AC020594
      UniProtKB/TrEMBL
      C9JD84
      Conserved Domains (3) summary
      smart00179
      Location:781 → 822
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:577 → 610
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:494 → 534
      EGF_CA; Calcium-binding EGF domain

    27. NM_206943.4 → NP_996826.3  latent-transforming growth factor beta-binding protein 1 isoform LTBP-1L precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (LTBP-1L). There are no full-length transcripts representing this variant in human, but it is supported by overlapping partial transcripts, full-length homologous rat and mouse transcripts, and data in PMID:8537398.
      Source sequence(s)
      AC019127, AC019195, AC020594, AL133244
      Consensus CDS
      CCDS33177.2
      UniProtKB/Swiss-Prot
      A1L3V1, P22064, Q14766, Q53SD8, Q53SF3, Q53SG1, Q59HF7, Q8TD95
      Related
      ENSP00000386043.2, ENST00000404816.7
      Conserved Domains (6) summary
      smart00179
      Location:1202 → 1243
      EGF_CA; Calcium-binding EGF-like domain
      PRK03427
      Location:751 → 865
      PRK03427; cell division protein ZipA; Provisional
      cd00054
      Location:998 → 1031
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:915 → 955
      EGF_CA; Calcium-binding EGF domain
      pfam00683
      Location:689 → 730
      TB; TB domain
      pfam12662
      Location:896 → 918
      cEGF; Complement Clr-like EGF-like

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      32946953..33399509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011532853.3 → XP_011531155.1  latent-transforming growth factor beta-binding protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q14766
      Conserved Domains (5) summary
      smart00179
      Location:1203 → 1244
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:999 → 1032
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 724
      TB; TB domain
      pfam07645
      Location:916 → 956
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:897 → 919
      cEGF; Complement Clr-like EGF-like

    2. XM_011532857.3 → XP_011531159.1  latent-transforming growth factor beta-binding protein 1 isoform X5

      Conserved Domains (5) summary
      smart00179
      Location:1203 → 1244
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:999 → 1032
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 724
      TB; TB domain
      pfam07645
      Location:916 → 956
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:897 → 919
      cEGF; Complement Clr-like EGF-like

    3. XM_011532861.3 → XP_011531163.1  latent-transforming growth factor beta-binding protein 1 isoform X20

      Conserved Domains (5) summary
      smart00179
      Location:1203 → 1244
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:999 → 1032
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 724
      TB; TB domain
      pfam07645
      Location:916 → 956
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:897 → 919
      cEGF; Complement Clr-like EGF-like

    4. XM_011532856.3 → XP_011531158.1  latent-transforming growth factor beta-binding protein 1 isoform X3

      Conserved Domains (4) summary
      smart00179
      Location:1163 → 1204
      EGF_CA; Calcium-binding EGF-like domain
      pfam00683
      Location:689 → 724
      TB; TB domain
      pfam07645
      Location:916 → 956
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:897 → 919
      cEGF; Complement Clr-like EGF-like

    5. XM_011532858.3 → XP_011531160.1  latent-transforming growth factor beta-binding protein 1 isoform X6

      Conserved Domains (4) summary
      smart00179
      Location:1161 → 1202
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:957 → 990
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 724
      TB; TB domain
      pfam07645
      Location:874 → 914
      EGF_CA; Calcium-binding EGF domain

    6. XM_017004109.2 → XP_016859598.1  latent-transforming growth factor beta-binding protein 1 isoform X7

    7. XM_047444368.1 → XP_047300324.1  latent-transforming growth factor beta-binding protein 1 isoform X21

    8. XM_017004108.2 → XP_016859597.1  latent-transforming growth factor beta-binding protein 1 isoform X4

    9. XM_017004110.2 → XP_016859599.1  latent-transforming growth factor beta-binding protein 1 isoform X15

    10. XM_047444359.1 → XP_047300315.1  latent-transforming growth factor beta-binding protein 1 isoform X8

    11. XM_047444366.1 → XP_047300322.1  latent-transforming growth factor beta-binding protein 1 isoform X18

    12. XM_047444364.1 → XP_047300320.1  latent-transforming growth factor beta-binding protein 1 isoform X16

    13. XM_011532855.3 → XP_011531157.1  latent-transforming growth factor beta-binding protein 1 isoform X2

      Conserved Domains (5) summary
      smart00179
      Location:1201 → 1242
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:997 → 1030
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 724
      TB; TB domain
      pfam07645
      Location:914 → 954
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:895 → 917
      cEGF; Complement Clr-like EGF-like

    14. XM_047444360.1 → XP_047300316.1  latent-transforming growth factor beta-binding protein 1 isoform X9

    15. XM_047444369.1 → XP_047300325.1  latent-transforming growth factor beta-binding protein 1 isoform X22

    16. XM_047444365.1 → XP_047300321.1  latent-transforming growth factor beta-binding protein 1 isoform X17

    17. XM_047444361.1 → XP_047300317.1  latent-transforming growth factor beta-binding protein 1 isoform X10

    18. XM_047444367.1 → XP_047300323.1  latent-transforming growth factor beta-binding protein 1 isoform X19

    19. XM_011532859.3 → XP_011531161.1  latent-transforming growth factor beta-binding protein 1 isoform X11

      Conserved Domains (5) summary
      smart00179
      Location:1150 → 1191
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:946 → 979
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 723
      TB; TB domain
      pfam07645
      Location:863 → 903
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:844 → 866
      cEGF; Complement Clr-like EGF-like

    20. XM_047444372.1 → XP_047300328.1  latent-transforming growth factor beta-binding protein 1 isoform X25

    21. XM_005264318.4 → XP_005264375.1  latent-transforming growth factor beta-binding protein 1 isoform X26

      Conserved Domains (5) summary
      smart00179
      Location:1149 → 1190
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:945 → 978
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:689 → 723
      TB; TB domain
      pfam07645
      Location:862 → 902
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:843 → 865
      cEGF; Complement Clr-like EGF-like

    22. XM_047444381.1 → XP_047300337.1  latent-transforming growth factor beta-binding protein 1 isoform X35

    23. XM_047444370.1 → XP_047300326.1  latent-transforming growth factor beta-binding protein 1 isoform X23

    24. XM_047444377.1 → XP_047300333.1  latent-transforming growth factor beta-binding protein 1 isoform X31

    25. XM_047444373.1 → XP_047300329.1  latent-transforming growth factor beta-binding protein 1 isoform X27

    26. XM_047444379.1 → XP_047300335.1  latent-transforming growth factor beta-binding protein 1 isoform X33

    27. XM_047444378.1 → XP_047300334.1  latent-transforming growth factor beta-binding protein 1 isoform X32

    28. XM_047444362.1 → XP_047300318.1  latent-transforming growth factor beta-binding protein 1 isoform X12

    29. XM_047444374.1 → XP_047300330.1  latent-transforming growth factor beta-binding protein 1 isoform X28

    30. XM_047444371.1 → XP_047300327.1  latent-transforming growth factor beta-binding protein 1 isoform X24

    31. XM_047444380.1 → XP_047300336.1  latent-transforming growth factor beta-binding protein 1 isoform X34

    32. XM_011532860.3 → XP_011531162.1  latent-transforming growth factor beta-binding protein 1 isoform X13

      Conserved Domains (5) summary
      smart00179
      Location:1147 → 1188
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:943 → 976
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00683
      Location:633 → 668
      TB; TB domain
      pfam07645
      Location:860 → 900
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:841 → 863
      cEGF; Complement Clr-like EGF-like

    33. XM_047444363.1 → XP_047300319.1  latent-transforming growth factor beta-binding protein 1 isoform X14

    34. XM_047444375.1 → XP_047300331.1  latent-transforming growth factor beta-binding protein 1 isoform X29

    35. XM_047444376.1 → XP_047300332.1  latent-transforming growth factor beta-binding protein 1 isoform X30

    36. XM_047444382.1 → XP_047300338.1  latent-transforming growth factor beta-binding protein 1 isoform X36

    37. XM_047444383.1 → XP_047300339.1  latent-transforming growth factor beta-binding protein 1 isoform X37

    38. XM_047444384.1 → XP_047300340.1  latent-transforming growth factor beta-binding protein 1 isoform X38

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      32992680..33445650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054342045.1 → XP_054198020.1  latent-transforming growth factor beta-binding protein 1 isoform X1

    2. XM_054342049.1 → XP_054198024.1  latent-transforming growth factor beta-binding protein 1 isoform X5

    3. XM_054342064.1 → XP_054198039.1  latent-transforming growth factor beta-binding protein 1 isoform X20

    4. XM_054342047.1 → XP_054198022.1  latent-transforming growth factor beta-binding protein 1 isoform X3

    5. XM_054342050.1 → XP_054198025.1  latent-transforming growth factor beta-binding protein 1 isoform X6

    6. XM_054342051.1 → XP_054198026.1  latent-transforming growth factor beta-binding protein 1 isoform X7

    7. XM_054342065.1 → XP_054198040.1  latent-transforming growth factor beta-binding protein 1 isoform X21

    8. XM_054342048.1 → XP_054198023.1  latent-transforming growth factor beta-binding protein 1 isoform X4

    9. XM_054342059.1 → XP_054198034.1  latent-transforming growth factor beta-binding protein 1 isoform X15

    10. XM_054342052.1 → XP_054198027.1  latent-transforming growth factor beta-binding protein 1 isoform X8

    11. XM_054342062.1 → XP_054198037.1  latent-transforming growth factor beta-binding protein 1 isoform X18

    12. XM_054342060.1 → XP_054198035.1  latent-transforming growth factor beta-binding protein 1 isoform X16

    13. XM_054342046.1 → XP_054198021.1  latent-transforming growth factor beta-binding protein 1 isoform X2

    14. XM_054342053.1 → XP_054198028.1  latent-transforming growth factor beta-binding protein 1 isoform X9

    15. XM_054342066.1 → XP_054198041.1  latent-transforming growth factor beta-binding protein 1 isoform X22

    16. XM_054342061.1 → XP_054198036.1  latent-transforming growth factor beta-binding protein 1 isoform X17

    17. XM_054342054.1 → XP_054198029.1  latent-transforming growth factor beta-binding protein 1 isoform X10

    18. XM_054342063.1 → XP_054198038.1  latent-transforming growth factor beta-binding protein 1 isoform X19

    19. XM_054342055.1 → XP_054198030.1  latent-transforming growth factor beta-binding protein 1 isoform X11

    20. XM_054342069.1 → XP_054198044.1  latent-transforming growth factor beta-binding protein 1 isoform X25

    21. XM_054342070.1 → XP_054198045.1  latent-transforming growth factor beta-binding protein 1 isoform X26

    22. XM_054342079.1 → XP_054198054.1  latent-transforming growth factor beta-binding protein 1 isoform X35

    23. XM_054342067.1 → XP_054198042.1  latent-transforming growth factor beta-binding protein 1 isoform X23

    24. XM_054342075.1 → XP_054198050.1  latent-transforming growth factor beta-binding protein 1 isoform X31

    25. XM_054342071.1 → XP_054198046.1  latent-transforming growth factor beta-binding protein 1 isoform X27

    26. XM_054342077.1 → XP_054198052.1  latent-transforming growth factor beta-binding protein 1 isoform X33

    27. XM_054342076.1 → XP_054198051.1  latent-transforming growth factor beta-binding protein 1 isoform X32

    28. XM_054342056.1 → XP_054198031.1  latent-transforming growth factor beta-binding protein 1 isoform X12

    29. XM_054342072.1 → XP_054198047.1  latent-transforming growth factor beta-binding protein 1 isoform X28

    30. XM_054342068.1 → XP_054198043.1  latent-transforming growth factor beta-binding protein 1 isoform X24

    31. XM_054342078.1 → XP_054198053.1  latent-transforming growth factor beta-binding protein 1 isoform X34

    32. XM_054342057.1 → XP_054198032.1  latent-transforming growth factor beta-binding protein 1 isoform X13

    33. XM_054342058.1 → XP_054198033.1  latent-transforming growth factor beta-binding protein 1 isoform X14

    34. XM_054342073.1 → XP_054198048.1  latent-transforming growth factor beta-binding protein 1 isoform X29

    35. XM_054342074.1 → XP_054198049.1  latent-transforming growth factor beta-binding protein 1 isoform X30

    36. XM_054342080.1 → XP_054198055.1  latent-transforming growth factor beta-binding protein 1 isoform X36

    37. XM_054342081.1 → XP_054198056.1  latent-transforming growth factor beta-binding protein 1 isoform X37

    38. XM_054342082.1 → XP_054198057.1  latent-transforming growth factor beta-binding protein 1 isoform X38

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q14766.4 GenPept UniProtKB/Swiss-Prot:Q14766

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