slc16a8 solute carrier family 16 member 8 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc16a8provided by ZNC
Official Full Name: solute carrier family 16 member 8provided by ZNC
Primary source: ZFIN:ZDB-GENE-121128-1
See related: Ensembl:ENSDARG00000045153 AllianceGenome:ZFIN:ZDB-GENE-121128-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to act upstream of or within monocarboxylic acid transport and transmembrane transport. Predicted to be located in membrane. Predicted to be active in basolateral plasma membrane. Is expressed in telencephalon. Orthologous to human SLC16A8 (solute carrier family 16 member 8). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (19191796..19198599)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (19071686..19076725)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
Title: Spatial expression and functional flexibility of monocarboxylate transporter isoforms in the zebrafish brain.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables monocarboxylic acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables monocarboxylic acid transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within monocarboxylic acid transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: monocarboxylate transporter 3

Names: solute carrier family 16 (monocarboxylate transporter), member 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001324527.1 → NP_001311456.1 monocarboxylate transporter 3

Status: VALIDATED

Source sequence(s)

BX000473

UniProtKB/TrEMBL

A0A8M9QMJ3, E7F4T7

Related

ENSDARP00000072787.4, ENSDART00000078325.6

Conserved Domains (1) summary

cl26868
Location:14 → 441

2A0111; oxalate/formate antiporter family transporter

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007123.7 Reference GRCz11 Primary Assembly

Range

19191796..19198599

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021480115.2 → XP_021335790.1 monocarboxylate transporter 3 isoform X1

UniProtKB/TrEMBL

A0A8M9QMJ3, E7F4T7

Related

ENSDARP00000127207.1, ENSDART00000152892.3

Conserved Domains (1) summary

cl26868
Location:14 → 441

2A0111; oxalate/formate antiporter family transporter