Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma [Methylation array]

Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

Capmatinib shows superior efficacy for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy.

Trophectoderm biopsies of blastocysts for preimplantation genetic testing following in vitro fertilization and embryo culture increases epigenetic dysregulation in a mouse model [array]

Trophectoderm biopsies of blastocysts for preimplantation genetic testing following in vitro fertilization and embryo culture increases epigenetic dysregulation in a mouse model

Impact of Folate Status on the Sperm DNA Methylome of Mice with the 677C>T Variant in 5,10-Methylenetetrahydrofolate Reductase

Maternal oxytocin treatment at birth increases epigenetic age in male offspring [array]

Maternal oxytocin treatment at birth increases epigenetic age in male offspring

Developmental priming of cancer susceptibility [DNA methylation array - d10earclips_2nd cohort]

Developmental priming of cancer susceptibility [DNA methylation array - healthyTissues]

Developmental priming of cancer susceptibility

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation [Array]

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) [MouseMethylation]

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD)

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions [Mouse Methylation285 12v1-0 BeadChip]

Optimizing the experimental and computational methods for Infinium DNA methylation BeadChip on low input and single cells

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions

Endocrine disruptor-induced epimutagenesis in vitro: Insight into molecular mechanisms [Infinium]

Endocrine disruptor-induced epimutagenesis in vitro: Insight into molecular mechanisms