Genome-Scale Exon Perturbation Screens Uncover Critical Exons for Cell Fitness

Non-Canonical BAF and mSWI/SNF Regulates POU2F3 and are Selective Targetable Dependencies for POU2F3-Positive Small Cell Lung Cancer

A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis

Cryptic splicing mediates genetic and therapeutic perturbation of human gene expression levels [Cut&Tag]

Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens in a dual fluorescence readthrough reporter

Regulation of IkB kinase family crosstalk by an N4BP1-caspase-8 axis

MERTK inhibition for the treatment of tissue fibrosis

Predisposal of Interferon Regulatory Factor 1 Deficiency to Accumulate DNA Damage and Promote Osteoarthritis Development in Cartilage

Suboptimization of human transcription factors

Transcriptional reprogramming of neural stem cells by a PHF6/EphR signalling pathway

TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing

Mechanical confinement governs phenotypic plasticity in melanoma

RNF20 contributes to epigenetic immunosuppression through CDK9-dependent LSD1 stablization

Cardiomyocyte ST-wave depression indel characterisation

Zfp281 and Zfp148 control CD4+ T cell thymic development and Th2 functions

Human histone H1 variants impact splicing outcome by controlling RNA polymerase II elongation rate.

The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A

cohesin spreads bi-directionally to form chromatin jets in C. elegans