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| Status |
Public on Nov 09, 2018 |
| Title |
Identification of gene signature in human colorectal CD44+ cancer stem cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We prospectively isolated human colorectal CD44+ cancer stem cells (CSCs) from organoids and primary colorectal cancer. The gene expression of CD44+ CSCs are relevant to each other between organoids and primary tissues. The common gene signature in two different modality identifies CSCs' properties with the biological significance shown in original article.
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| |
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| Overall design |
Gene expression profiles of primary colorectal cancer cells and organoids, which were purified into CD44- and CD44+ fraction by cell sorting, were analyzed.
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| |
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| Contributor(s) |
Nakano M, Miyawaki K |
| Citation(s) |
30181548 |
| |
| Submission date |
Jun 23, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Michitaka Nakano |
| Organization name |
Kyushu University
|
| Department |
Department of Medicine and Biosystemic Sciences
|
| Street address |
3-1-1, Maidashi, Higashi-ku
|
| City |
Fukuoka |
| State/province |
Fukuoka |
| ZIP/Postal code |
812-8582 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA391725 |
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