|
| Status |
Public on Jan 01, 2018 |
| Title |
PUVA pretreatment leads to significant reduction in imiquimod induced psoriatic phenotype with gene expression signature associated with senescence |
| Platform organism |
Mus musculus |
| Sample organism |
Mus |
| Experiment type |
Expression profiling by array
|
| Summary |
PUVA pretreatment leads to develop early senescence confirmed by p16, p21 and SA-β-GAL positivity which was completely normalised by longer gap.
Indicating that PUVA pretreatment causes conditioning set of genes that led to a marked delay in psoriasis development.
|
| |
|
| Overall design |
To study the induction and phenotypes development of Aldara-mediated dermatitis in mice pretreated with PUVA in comparison to UVB
|
| |
|
| Contributor(s) |
Shirsath N, Wagner K, Schlederer M, Kenner L, Wolf P |
| Citation(s) |
29582898 |
| |
| Submission date |
Jul 04, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Karin Wagner |
| E-mail(s) |
kar.wagner@medunigraz.at
|
| Organization name |
Medical University Graz
|
| Department |
Molecular Biology
|
| Street address |
Stiftingtalstrasse 24
|
| City |
Graz |
| State/province |
Styria |
| ZIP/Postal code |
8010 |
| Country |
Austria |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA393005 |
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