|
| Status |
Public on Jan 18, 2018 |
| Title |
Mitotic chromosomes fold by condensin-dependent helical winding of chromatin loop arrays |
| Organisms |
Gallus gallus; Homo sapiens |
| Experiment type |
Other
|
| Summary |
Mitotic chromosome morphogenesis occurs through condensin-mediated disassembly of the interphase conformation and formation of extended prophase loop arrays that then shorten by condensin-dependent helical winding
|
| |
|
| Overall design |
Chromosome organization investigation through Hi-C
|
| Web link |
http://science.sciencemag.org/content/early/2018/01/17/science.aao6135
|
| |
|
| Contributor(s) |
Gibcus JH, Goloborodko A, Samejima K, Samejima I, Naumova N, Kanemaki MT, Xie L, Paulson JR, Earnshaw WC, Mirny L, Dekker J |
| Citation(s) |
29348367 |
| |
| Submission date |
Aug 16, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Job Dekker |
| Organization name |
UMass Medical School
|
| Department |
Program in Systems Biology
|
| Lab |
Dekker Labaratory
|
| Street address |
368 Plantation Street
|
| City |
Worcester |
| State/province |
Massachusetts |
| ZIP/Postal code |
01605 |
| Country |
USA |
| |
|
| Platforms (3) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL16133 |
Illumina HiSeq 2000 (Gallus gallus) |
| GPL23499 |
Illumina HiSeq 4000 (Gallus gallus) |
|
| Samples (60)
|
|
| Relations |
| BioProject |
PRJNA398543 |
| SRA |
SRP115572 |
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