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| Status |
Public on Nov 21, 2017 |
| Title |
Whole genome RNA-seq analysis of Wild type or Elf4-/- peritoneal macrophages and whole genome RNA-seq analysis of 293T cells transfected with miR-221 or empty vector. |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Wild type or Elf4-/- peritoneal macrophages were infected with VSV, followed by whole genome RNA-seq analysis. 293T cells were transfected with miR-221 or empty vector, followed by whole genome RNA-seq analysis.
Conclusions:Overexpression of miR-221 in cells facilitated viral infection and inhibited the production of IFNβ.
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| Overall design |
Wild type or Elf4-/- peritoneal macrophages were infected with VSV for 4 hours. Cells were harvested followed by whole genome RNA-seq analysis. 293T cells were transfected with miR-221 or empty vector. 6 hours later the cells were were harvested followed by whole genome RNA-seq analysis.
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| |
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| Contributor(s) |
Cao L, You F |
| Citation(s) |
30890658 |
| Submission date |
Nov 20, 2017 |
| Last update date |
Dec 16, 2019 |
| Contact name |
lili Cao |
| E-mail(s) |
caolili@bjmu.edu.cn
|
| Organization name |
Peking university health science center
|
| Street address |
Xueyuan road, haidian district
|
| City |
Beijing |
| ZIP/Postal code |
100191 |
| Country |
China |
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| Platforms (2) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA419209 |
| SRA |
SRP125326 |
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