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| Status |
Public on Jan 05, 2018 |
| Title |
Comparison of gene expression in the GAS M1T1 strain 5448, wild-type vs pepO mutant |
| Organism |
Streptococcus pyogenes |
| Experiment type |
Expression profiling by array
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| Summary |
Manuscript title: The endopeptidase PepO regulates the SpeB cysteine protease and is essential for the virulence of invasive M1T1 Streptococcus pyogenes.
The study investigates the effect of pepO mutation on global gene expression in GAS M1T1 strain 5448.
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| Overall design |
Two-condition experiment, GAS M1T1 strain 5448 WT vs. pepO mutant. Biological replicates: 3, independently grown and harvested. One replicate of each strain per array.
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| Contributor(s) |
Brouwer S, Cork AJ, Ong CL, Barnett TC, West NP, McIver KS, Walker MJ |
| Citation(s) |
29378883 |
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| Submission date |
Jan 04, 2018 |
| Last update date |
Apr 08, 2018 |
| Contact name |
Stephan Brouwer |
| E-mail(s) |
s.brouwer@uq.edu.au
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| Organization name |
The University of Queensland
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| Department |
School of Chemistry and Molecular Biosciences
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| Lab |
Walker Lab
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| Street address |
Cooper Road, Building 76, Rm 151
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| City |
St Lucia |
| State/province |
QLD |
| ZIP/Postal code |
4072 |
| Country |
Australia |
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| Platforms (1) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA428486 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE108748_RAW.tar |
13.0 Mb |
(http)(custom) |
TAR (of TXT, XLSX) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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