|
| Status |
Public on Jun 05, 2018 |
| Title |
ZNF281 inhibits neuronal differentiation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Derangement of cellular differentiation due to mutation or inappropriate expression of specific genes is a common feature in tumours. Here, we show that depletion of ZNF281 induces neuronal differentiation of neuroblastoma cells.
|
| |
|
| Overall design |
To investigate the effect of ZNF281 depletion on neuronal differentiation, we used microarray expression profiling to identify the genes with altered expression. Human neuroblastoma cells BE2(M17) were transiently knocked-down by RNA interference.
|
| |
|
| Contributor(s) |
Pitolli C, Nicolai S |
| Citation(s) |
29941555 |
| |
| Submission date |
Mar 19, 2018 |
| Last update date |
Jun 27, 2018 |
| Contact name |
Artem Smirnov |
| E-mail(s) |
art.smirnow@gmail.com
|
| Organization name |
University of Rome "Tor Vergata"
|
| Department |
Dept. of Exp. Medicine and Surgery
|
| Lab |
Molecular biology lab (Prof. G. Melino)
|
| Street address |
Via Montpellier, 1
|
| City |
Rome |
| ZIP/Postal code |
00133 |
| Country |
Italy |
| |
|
| Platforms (1) |
| GPL21185 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name Version] |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA438998 |
Less...
More...