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| Status |
Public on Apr 18, 2018 |
| Title |
Gene expression signatures for murine stromal cells from tumor-draining lymph nodes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To determine the influence of primary tumors on pre-metastatic lymph nodes, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of stromal cells from tumor-draining lymph nodes, compared with normal lymph nodes. We subcutaneously inoculated C57BL/6 mice with the 4T1 mammary carcinoma. Two weeks later, tumor-draining lymph nodes were dissociated and stromal cells (CD45-) were sorted. Lymph nodes stromal cells from normal mice without tumor bearing were set as controls.
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| Overall design |
Primary tumor induced gene expression in stromal cells from tumor-draining lymph nodes was measured at 2 weeks after tumor inoculation subcutaneously. Lymph nodes stromal cells from normal mice without tumor bearing were set as controls.
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| Contributor(s) |
Cao X, Gu Y |
| Citation missing |
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| Submission date |
Apr 17, 2018 |
| Last update date |
Apr 20, 2018 |
| Contact name |
Yan Gu |
| E-mail(s) |
guyan_84@163.com
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| Phone |
0086-13564879086
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| Organization name |
Second Miilitary Medical University
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| Department |
Immunology
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| Street address |
800 Xiangyin Road
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| City |
Shanghai |
| ZIP/Postal code |
200433 |
| Country |
China |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA450551 |
