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| Status |
Public on May 13, 2008 |
| Title |
Expression Data From HCMV-Infected Human Monocytes Study 2 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Human cytomegalovirus induces a pro-inflammatory monocyte following infection. To begin to address how HCMV induces these rapid changes in infected monocytes, we examined the transcriptome of infected monocytes. Global transcriptional profiling using cDNA microarrays revealed a significant number of pro-inflammatory genes were upregulated within 4 hours post infection.
Keywords: Disease State
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| Overall design |
To begin to globally define the HCMV-induced changes in monocyte function, we performed a transcriptome analysis. Specifically, a cDNA microarray containing 12,626 unique probe sets was utilized to assess the modulation of the monocyte transcriptome at 4 hours post infection. A total of 6 replicates from mock-infected and 6 replicates from HCMV-infected monocytes were analyzed in this study.
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| Contributor(s) |
Chan G, Bivins-Smith ER, Smith MS, Yurochko AD |
| Citation(s) |
18566437, 20173022 |
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| Submission date |
May 09, 2008 |
| Last update date |
Dec 13, 2018 |
| Contact name |
Andrew D. Yurochko |
| E-mail(s) |
ayuroc@lsuhsc.edu
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| Phone |
318-675-8332
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| Fax |
318-675-5764
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| Organization name |
LSUHSC-S
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| Department |
Microbiology & Immunology
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| Street address |
1501 Kings Highway
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| City |
Shreveport |
| State/province |
LA |
| ZIP/Postal code |
71130-3932 |
| Country |
USA |
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| Platforms (1) |
| GPL8300 |
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA106539 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE11408_RAW.tar |
39.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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