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Series GSE114958 Query DataSets for GSE114958
Status Public on Dec 13, 2018
Title Virus-mediated export of chromosomal DNA in plants
Organisms Arabidopsis thaliana; Beta vulgaris
Experiment type Other
Summary The propensity of viruses to acquire genetic material from relatives and possibly from infected hosts makes them excellent candidates as vectors for horizontal gene transfer. However, virus-mediated acquisition of host genetic material, as deduced from historical events, appears to be rare. Here, we report spontaneous and surprisingly efficient generation of hybrid virus/host DNA molecules in the form of minicircles during infection of Beta vulgaris by Beet curly top Iran virus (BCTIV), a single-stranded DNA virus. The hybrid minicircles replicate, become encapsidated into viral particles, and spread systemically throughout infected plants in parallel with the viral infection. Importantly, when co-infected with BCTIV, B. vulgaris DNA captured in minicircles replicate and is transcribed in other plant species that are sensitive to BCTIV infection. Thus, we have likely documented in real time the initial steps of a possible path of virus-mediated horizontal transfer of chromosomal DNA between plant species.
Overall design DNA re-sequencing of BCTIV-infected Arabidopsis and Beta vulgaris plants, and a healthy mock-inoculated Beet control.
Contributor(s) Catoni M
Citation(s) 30546019
Submission date May 28, 2018
Last update date Dec 20, 2018
Contact name Marco Catoni
Organization name University of Birmingham
Department School of Biosciences
Street address Edgbaston
City Birmingham
ZIP/Postal code B15 2TT
Country United Kingdom
Platforms (2)
GPL19580 Illumina NextSeq 500 (Arabidopsis thaliana)
GPL25041 Illumina NextSeq 500 (Beta vulgaris)
Samples (4)
GSM3160810 Bvulgaris_BT
GSM3160811 Bvulgaris_HH
GSM3160812 At_BT_rep1
BioProject PRJNA473337
SRA SRP149078

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE114958_Bvulgaris_BT_filtered_scaffolds.fasta.gz 2.0 Kb (ftp)(http) FASTA
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Raw data are available in SRA
Processed data are available on Series record

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