|
| Status |
Public on Jun 25, 2018 |
| Title |
Identification of Exosome-Like Nanoparticle Derived MicroRNAs from Eleven Edible Plants |
| Organisms |
Actinidia chinensis; Cucumis melo; Pyrus; Glycine max; Pisum sativum; Solanum lycopersicum; Vaccinium; Cocos nucifera; Citrus x paradisi; Citrus reticulata; Zingiber officinale |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
In this study, we found that the highly expressed miRNAs appear in EPDELNs (Edible plant-derived exosome-like nanoparticles) have the potential to regulate human mRNA in a cross-kingdom manner. Target prediction and functional analysis revealed that highly expressed miRNAs were closely associated with inflammatory responses and cancer-related pathways. Therefore, we hypothesized that miRNAs in EPDELNs may be a crucial factor behind the regulatory function of EPDELNs.
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| |
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| Overall design |
We investigated miRNA expression profiles from 11 EPDELNs (Blueberry; Coconut; Ginger; Grapefruit; Hami melon; Kiwifruit; Pea; Orange; Pear; Soybean; Tomato) by using high-throughput sequencing technology.
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| |
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| Contributor(s) |
Xiao J, Feng S |
| Citation missing |
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| |
| Submission date |
Jun 20, 2018 |
| Last update date |
Feb 07, 2019 |
| Contact name |
Juan Xiao |
| E-mail(s) |
XiaoJuan751190178@163.com
|
| Phone |
18283582445
|
| Organization name |
Sichuan Agricultural University
|
| Department |
Institute of Animal Genetics and Breeding, College of Animal Science and Technology
|
| Lab |
The Laboratory of swine
|
| Street address |
Huimin road No.211, Wenjiang
|
| City |
Chengdu |
| State/province |
Sichuan |
| ZIP/Postal code |
611130 |
| Country |
China |
| |
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| Platforms (11)
|
| GPL19246 |
Illumina HiSeq 2500 (Glycine max) |
| GPL19694 |
Illumina HiSeq 2500 (Solanum lycopersicum) |
| GPL25219 |
Illumina HiSeq 2500 (Vaccinium) |
| GPL25220 |
Illumina HiSeq 2500 (Cocos nucifera) |
| GPL25221 |
Illumina HiSeq 2500 (Zingiber officinale) |
| GPL25222 |
Illumina HiSeq 2500 (Citrus x paradisi) |
| GPL25223 |
Illumina HiSeq 2500 (Cucumis melo) |
| GPL25224 |
Illumina HiSeq 2500 (Actinidia chinensis) |
| GPL25225 |
Illumina HiSeq 2500 (Pisum sativum) |
| GPL25226 |
Illumina HiSeq 2500 (Citrus reticulata) |
| GPL26168 |
Illumina HiSeq 2500 (Pyrus) |
|
| Samples (11)
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| Relations |
| BioProject |
PRJNA477334 |
| SRA |
SRP151038 |
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