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Series GSE120103 Query DataSets for GSE120103
Status Public on Feb 26, 2019
Title Homo sapiens whole genome expression microarray of endometrium obtained from fertile and Infertile women with stage IV ovarian endometriosis and without endometriosis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The hypothesis that male michrochimerism in eutopic endometrium is a factor for endometriosis, as indicated by indirect evidence was examined in endometrial samples from control (Group 1) and stage IV ovarian endometriosis (Group 2), either fertile (Group 1A and 2A) or Infertile (Group 1B and 2B) pateints.
6 coding and 10 non-coding genes showed bi-modal pattern of expression characterised by low expression in samples obtained from fertile patients and high expressions in infertile patients. Several coding and non-coding MSY-linked genes displayed michrochimerism in form of presence of their respective DNA inserts along with their microarray-detectable expression in endometrium irrespective of fertility history and disease.
 
Overall design Whole genome expression arrays of endometrial total RNA obtained from endometrium of women without endometriosis (Group 1) and with stage IV ovarian endometriosis (Group 2), either fertile (Group 1A and 2A) or Infertile (Group 1B and 2B).
 
Contributor(s) Bhat MA, Ghosh D
Citation(s) 30760267
Submission date Sep 18, 2018
Last update date Feb 26, 2019
Contact name Muzaffer Ahmed Bhat
E-mail(s) muzaffar.sciml87@gmail.com
Phone 91 8826753204
Organization name AIIMS
Department Physiology
Lab Molecular Biology
Street address ANSARI NAGAR NEW DELHI 110029
City Delhi
State/province Delhi
ZIP/Postal code 110029
Country India
 
Platforms (1)
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Samples (36)
GSM3393491 Disease free Endometrium of fertile women, replicate 1
GSM3393492 Disease free Endometrium of fertile women, replicate 2
GSM3393493 Disease free Endometrium of fertile women, replicate 3
Relations
BioProject PRJNA491703

Download family Format
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE120103_RAW.tar 104.2 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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