|
| Status |
Public on Jun 27, 2019 |
| Title |
Study of MeCP2 binding and accessibity of chromatin in absence and presence of MeCP2 using ATAC-seq |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
ATAC-seq was performed to study changes in chromatin openness in the MeCP2 knock-outs and overexpressions. Additionally data was used to visualise the foorprint of MeCP2 bound to chromatin in vivo.
|
| |
|
| Overall design |
ATAC-seq was performed on LUHMES-derived neurons including: controls, MeCP2 KO and OE.
|
| |
|
| Contributor(s) |
Cholewa-Waclaw J, Webb S |
| Citation(s) |
31289233, 32064528 |
| |
| Submission date |
Jan 25, 2019 |
| Last update date |
Apr 20, 2020 |
| Contact name |
Shaun Michael Webb |
| E-mail(s) |
shaun.webb@ed.ac.uk
|
| Organization name |
University of Edinburgh
|
| Department |
Wellcome Trust Centre for Cell Biology
|
| Lab |
Bioinformatics Core Facility
|
| Street address |
2.21 Swann Building, Kings Buildings
|
| City |
Edinburgh |
| ZIP/Postal code |
EH9 3JR |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (13)
|
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| This SubSeries is part of SuperSeries: |
| GSE125660 |
Study of MeCP2 in LUHMES-derived neurons |
|
| Relations |
| BioProject |
PRJNA517118 |
| SRA |
SRP182052 |
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