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Series GSE12986 Query DataSets for GSE12986
Status Public on Feb 01, 2010
Title Expression of Cdx2 or Gata3 in R1 mouse embryonic stem cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary To identify whether Cdx2 or Gata3 can activate trophoblast specific gene expression when expressed in R1 ES cells. To assess the dependency of Gata3 activity on Cdx2, Gata3 was also expressed in Cdx2-null ES cells.

Keywords: gene expression
Overall design a fusion construct of either Cdx2 or Gata3 and the tamoxifen responsive estrogen receptor ligand binding domain was expressed in R1 ES cells. Cell were induced with tamoxifen for 6 days to activate the transcription factor and cultured under trophoblast stem cell conditions
Contributor(s) Cox B, Ralston A, Rossant J
Citation(s) 20081188
Submission date Sep 30, 2008
Last update date Feb 11, 2019
Contact name Brian Joseph Cox
Organization name University of Toronto
Department Physiology
Lab Cox System Biology
Street address 1 King's College Circle, Rm 3360
City Toronto
State/province Ontario
ZIP/Postal code M5S1A8
Country Canada
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (10)
GSM325450 Gata3_H4
GSM325451 Gata3_A3
GSM325452 Gata3_D3
This SubSeries is part of SuperSeries:
GSE12999 Gata3 acts alongside Cdx2 to promote trophoblast gene expression downstream of Tead4 during mouse development
BioProject PRJNA114249

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE12986_RAW.tar 44.2 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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