|
| Status |
Public on Jun 13, 2019 |
| Title |
Melatonin protects against defects induced by malathion during porcine oocyte maturation |
| Organism |
Sus scrofa |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We used porcine oocytes as model and found that MAL exposure significantly impaired porcine oocyte maturation in a dose dependent manner. RNA-seq analyses showed that MAL altered the mRNA level of 2917 genes in the porcine maturated oocytes and most of these genes were related to ROS, the lipid droplet process and the energy supplement.
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| |
|
| Overall design |
RNA-seq analysis was used to investigate how MAL affects intracellular stored mRNA in oocytes
|
| Web link |
https://onlinelibrary.wiley.com/doi/10.1002/jcp.29189
|
| |
|
| Contributor(s) |
Chen L, Zhang J, Miao Y |
| Citation(s) |
31535366 |
| |
| Submission date |
Jun 12, 2019 |
| Last update date |
Jan 09, 2023 |
| Contact name |
Jing-Jing Zhang |
| E-mail(s) |
jjzhang@webmail.hzau.edu.cn
|
| Organization name |
Huazhong Agricultural University
|
| Department |
Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction
|
| Lab |
Miaolab
|
| Street address |
1 Lion Rock Street
|
| City |
Wuhan |
| State/province |
Hubei |
| ZIP/Postal code |
430070 |
| Country |
China |
| |
|
| Platforms (1) |
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| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA548540 |
| SRA |
SRP201217 |
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