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| Status |
Public on Dec 01, 2020 |
| Title |
Analysis of Escherichia coli adaptation to a sublethal concentration of sodium bisulfite |
| Organism |
Escherichia coli str. K-12 substr. MG1655 |
| Experiment type |
Expression profiling by array
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| Summary |
Little is known about cell responses and survival in the presence if reducing agents that could change the redox state of living organisms potentially conferring a negative effect on major metabolic pathways and respiration. As many reducing reagents, in particular sulfur-containing compounds, are widely used as food preservatives, we decided to study effects of sublethal concentrations of reducing reagents on bacterial adaptation.
The aim of this study was to analyse and compare the transcriptome profils of untreated and sulfite-treated Escherichia coli cells obtained by employing microarray analysis.
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| Overall design |
Total RNA was isolated from Echerichia coli MG1655 cultures grown in M9 supplemented with 0.4% glucose prior and after sulfite treatment and submited for microarray analysis
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| Contributor(s) |
Kaberdin VR, Montánchez I, Recio IA, Plágaro AH |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 23, 2019 |
| Last update date |
Dec 20, 2020 |
| Contact name |
Ander Hernández Plágaro |
| Organization name |
University of the Basque Country
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| Department |
Immunology, Microbiology and Parasitology
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| Lab |
Bacterial response to stress
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| Street address |
Barrio Sarriena S/N
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| City |
Leioa |
| State/province |
Bizkaia |
| ZIP/Postal code |
48940 |
| Country |
Spain |
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| Platforms (1) |
| GPL27511 |
Agilent-032948 E. coli Gene Expression Microarray_VK1 020097 |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA573708 |
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