|
| Status |
Public on Jan 10, 2009 |
| Title |
Microarray Analysis of Toxicogenomic Effects of Chlorhexidine diacetate on Pseudomonas aeruginosa |
| Organism |
Pseudomonas aeruginosa |
| Experiment type |
Expression profiling by array
|
| Summary |
In the present study, we employed Affymetrix Pseudomonas aeruginosa GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Pseudomonas aeruginosa to Chlorhexidine diacetate, which involved initial growth inhibition and metabolism.
Keywords: Transcriptome study
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| |
|
| Overall design |
We conducted three independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of Chlorhexidine diacetate. We calculated fold change as the ratio between the signal averages of three untreated (control) and three chlorhexidine diacetate-treated (experimental) cultures for 0, 10 and 60 min exposures.
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| |
|
| Contributor(s) |
Nde C, Toghrol F, Bentley WE |
| Citation(s) |
19924977 |
| Submission date |
Dec 31, 2008 |
| Last update date |
Jul 06, 2016 |
| Contact name |
Chantal Wheko Nde |
| Organization name |
USEPA
|
| Department |
OPP/BEAD
|
| Lab |
MARL
|
| Street address |
701 Mapes Road
|
| City |
Fort Meade |
| State/province |
MD |
| ZIP/Postal code |
20755 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL84 |
[Pae_G1a] Affymetrix Pseudomonas aeruginosa Array |
|
| Samples (9)
|
| GSM356956 |
Chlorhexidine diacetate_10min_replicate1 |
| GSM356957 |
Chlorhexidine diacetate_10min_replicate2 |
| GSM356958 |
Chlorhexidine diacetate_10min_replicate3 |
| GSM356959 |
Chlorhexidine diacetate_60min_replicate1 |
| GSM356960 |
Chlorhexidine diacetate_60min_replicate2 |
| GSM356961 |
Chlorhexidine diacetate_60min_replicate3 |
|
| Relations |
| BioProject |
PRJNA111325 |
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