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| Status |
Public on Aug 04, 2022 |
| Title |
HDAC inhibition suppresses telomerase activity in neuroblastoma cells harboring TERT rearrangements [array] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
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| Summary |
Genome wide DNA methylation profiling of high-risk TERT-rearranged neuroblastoma cells treated with solvent or HDAC inhibitor panobinostat. The Illumina HumanMethylation EPIC Beadchip was used to obtain DNA methylation profiles. Samples included 3 solvent treated samples and 3 panobinostat-treated samples after 18 h of treatment.
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| Overall design |
Bisulphite converted DNA from the 6 samples were hybridised to the Illumina HumanMethylation EPIC Beadchip
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| Contributor(s) |
Finkler S, Weiner J, Helmsauer K, Sprüssel A, Arlt B, Kuenkele A, Schulte JH, Haase K, Obermayer B, Beule D, Fischer M, Bluethgen N, Henssen AG, Lodrini M, Eggert A, Deubzer HE |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Aug 04, 2020 |
| Last update date |
Jan 06, 2023 |
| Contact name |
January 3rd Weiner |
| E-mail(s) |
january.weiner@gmail.com
|
| Phone |
030450543049
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| Organization name |
Berlin Institute of Health, Charité Medical University of Berlin
|
| Department |
CUBI
|
| Street address |
Charitéplatz 1
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| City |
Berlin |
| ZIP/Postal code |
10117 |
| Country |
Germany |
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| Platforms (1) |
| GPL23976 |
Illumina Infinium HumanMethylation850 BeadChip |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE155707 |
HDAC inhibition suppresses telomerase activity in neuroblastoma cells harboring TERT rearrangements |
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| Relations |
| BioProject |
PRJNA655243 |
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