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Status |
Public on Apr 01, 2021 |
Title |
Expression data from early postnatal brain in autism model marmoset |
Organism |
Callithrix jacchus |
Experiment type |
Expression profiling by array
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Summary |
Autism spectrum disorder (ASD) affects gene expression in early postnatal development. We used valproic acid (VPA)-induced ASD model marmosets. Gene expression in VPA-exposed and unexposed (UE) marmosets were analyzed at 0, 3 and 6 months (M). We revealed three groups of differentially expressed genes based on the temporal patterns of modulation.
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Overall design |
Tissues from three cortical areas (Brodmann area 8, 12, and TE) of UE and VPA marmosets were isolated. RNA was extracted and hybridized on custom-made microarrays. We sought to obtain differentially expressed genes at each age.
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Contributor(s) |
Oga T, Sasaki T, Sumida K, Hoshino K, Saito K, Miyawaki I, Nakagaki K, Watanabe S, Ichinohe N |
Citation(s) |
34526497 |
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Submission date |
Aug 13, 2020 |
Last update date |
Oct 08, 2021 |
Contact name |
Satoshi Watanabe |
Organization name |
National Center of Neurology and Psychiatry
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Street address |
4-1-1 Ogawa Higashi
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City |
Kodaira |
State/province |
Tokyo |
ZIP/Postal code |
187-8502 |
Country |
Japan |
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Platforms (1) |
GPL29019 |
[Marmo2a520631F] Affymetrix Custom Marmoset GeneChip |
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Samples (51)
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Relations |
BioProject |
PRJNA657011 |