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Series GSE15650 Query DataSets for GSE15650
Status Public on Apr 10, 2010
Title Comparative Genome Hybridization Reveals Few Genetic Differences between Aspergillus flavus and A. oryzae
Platform organisms Zea mays; Aspergillus flavus; Aspergillus oryzae
Sample organisms Aspergillus flavus; Aspergillus oryzae
Experiment type Genome variation profiling by array
Summary Aspergillus flavus and A. oryzae represent two unique species predicted to have spent centuries in vastly different environments. A. flavus is an important opportunistic plant pathogen known for contaminating crops with the carcinogenic mycotoxin, aflatoxin and A. oryzae is a domesticated fungus used in food fermentations. Remarkably, the genomes of these two species are still nearly identical. We have used the recently sequenced genomes of A. oryzae RIB40 and A. flavus NRRL3357 along with array based comparative genome hybridization (CGH) as a tool to compare genomes across several strains of these two species. A comparison of three strains from each species by CGH revealed only 42 and 129 genes unique to A. flavus and A. oryzae, respectively. Further, only 709 genes were identified as being polymorphic between the species. Despite the high degree of similarity between these two species, correlation analysis among all data from the CGH arrays for all strains used in this study reveals a species split. However, this view of species demarcation becomes muddled when focused on only those genes for secondary metabolism.
Overall design CGH comparison between 3 strains of A. flavus and 3 strains of A. oryzae, analyzed at the probe level
Contributor(s) Georgianna DR, Payne GA, Woloshuk CP, Keller NP, Yu J
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Submission date Apr 13, 2009
Last update date Oct 02, 2014
Contact name David Ryan Georgianna
Phone 919-515-6995
Organization name North Carolina State University
Department Plant Pathology
Lab Center for Integrated Fungal Research - Gary Payne
Street address 851 Main Campus Dr
City Raleigh
State/province NC
ZIP/Postal code 27695
Country USA
Platforms (1)
GPL8345 [Flavus_22683_AFLAVUSa520391F] NCSU Payne_Aspergillus Array
Samples (6)
GSM391668 NRRL3357
GSM391669 RIB40
GSM391670 NRRL1957
BioProject PRJNA116665

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE15650_RAW.tar 21.9 Mb (http)(custom) TAR (of CEL)
GSE15650_loess_normalized.xls.gz 10.2 Mb (ftp)(http) XLS
Processed data are available on Series record

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