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Series GSE156664 Query DataSets for GSE156664
Status Public on Aug 21, 2023
Title Next Generation Sequencing Facilitates Quantitative Analysis of Canine Cytotoxic T Cells Transcriptome
Organism Canis lupus familiaris
Experiment type Expression profiling by high throughput sequencing
Summary This study aims to investigate the functions of cDLBCL-derived exosomes on cytotoxic T cells among peripheral blood mononuclear cells (PBMCs) in healthy dogs. Through RNA next-generation sequencing (NGS) and bioinformatics. Reveal the differences between the two groups with or without exosomes treatment. It includes the gene function list, protein profiles, the differentially expressed genes, the biological pathways, and the analysis of networks.
 
Overall design Harvested canine CD8+ T cells to perform Transcriptome Next Generation Sequencing after co-culturing with 50 ug/ mL lymphoma exosomes for 48 hours. And vehicle controls were parallel treated with PBS. The results include two independent repeated experiments (N=2, N means the numbers of the samples from healthy dogs).
 
Contributor(s) Lin C, Weng H
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Aug 21, 2020
Last update date Aug 21, 2023
Contact name Chen-Si Lin
E-mail(s) cslin100@ntu.edu.tw
Organization name Nationwide Taiwan University
Department Department of Veterinary Medicine
Lab Lab of Clinical Pathology and Cancer Research
Street address No. 1, Sec. 4, Roosevelt Road
City Taipei
ZIP/Postal code 10617
Country Taiwan
 
Platforms (1)
GPL25760 Illumina NovaSeq 6000 (Canis lupus familiaris)
Samples (4)
GSM4736392 Control_N1
GSM4736393 Treat_N1
GSM4736394 Control_N2
Relations
BioProject PRJNA658600
SRA SRP278421

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE156664_Treat_N1.Control_N1.DEGseq_DEG_Summary.xlsx 1.6 Mb (ftp)(http) XLSX
GSE156664_Treat_N2.Control_N2.DEGseq_DEG_Summary.xlsx 1.5 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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