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Status |
Public on Jan 05, 2011 |
Title |
p73 activity and rapamycin treatment: ChIP-on-Chip and gene expression profiling studies |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array Genome binding/occupancy profiling by genome tiling array
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Summary |
p73 is a p53 family transcription factor that plays critical roles during development and tumor suppression. We analyzed p73 activity using a combination of ChIP-on-Chip and gene expression profiling, both at baseline and after treatment with the mTOR inhibitor rapamycin.
This SuperSeries is composed of the SubSeries listed below.
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Overall design |
Refer to individual Series
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Contributor(s) |
Rosenbluth JM, Pietenpol JA |
Citation(s) |
21245298 |
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Submission date |
Apr 17, 2009 |
Last update date |
Jul 26, 2018 |
Contact name |
Jennifer Pietenpol |
Organization name |
Vanderbilt University Medical Center
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Department |
Biochemistry
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Lab |
652 PRB
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Street address |
23rd Ave South at Pierce
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City |
Nashville |
State/province |
TN |
ZIP/Postal code |
37232 |
Country |
USA |
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Platforms (8)
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GPL4910 |
[Hs35b_P01R] Affymetrix Human Tiling 2.0R Set, Array 1 |
GPL4911 |
[Hs35b_P02R] Affymetrix Human Tiling 2.0R Set, Array 2 |
GPL4912 |
[Hs35b_P03R] Affymetrix Human Tiling 2.0R Set, Array 3 |
GPL4913 |
[Hs35b_P04R] Affymetrix Human Tiling 2.0R Set, Array 4 |
GPL4914 |
[Hs35b_P05R] Affymetrix Human Tiling 2.0R Set, Array 5 |
GPL4915 |
[Hs35b_P06R] Affymetrix Human Tiling 2.0R Set, Array 6 |
GPL4916 |
[Hs35b_P07R] Affymetrix Human Tiling 2.0R Set, Array 7 |
GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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Samples (22)
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GSM393164 |
Vehicle control, sh p73-2, B |
GSM393165 |
40 nM rapamycin, sh GFP, A |
GSM393166 |
40 nM rapamycin, sh GFP, B |
GSM393167 |
40 nM rapamycin, sh p73-1, A |
GSM393168 |
40 nM rapamycin, sh p73-2, B |
GSM393169 |
p73_ChIP_Veh_A |
GSM393170 |
p73_ChIP_Veh_B |
GSM393171 |
p73_ChIP_Veh_C |
GSM393172 |
p73_ChIP_Veh_D |
GSM393173 |
p73_ChIP_Veh_E |
GSM393174 |
p73_ChIP_Veh_F |
GSM393175 |
p73_ChIP_Veh_G |
GSM393176 |
p73_ChIP_Rap_A |
GSM393177 |
p73_ChIP_Rap_B |
GSM393178 |
p73_ChIP_Rap_C |
GSM393179 |
p73_ChIP_Rap_D |
GSM393180 |
p73_ChIP_Rap_E |
GSM393181 |
p73_ChIP_Rap_F |
GSM393182 |
p73_ChIP_Rap_G |
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This SuperSeries is composed of the following SubSeries: |
GSE15703 |
Expression data from rapamycin treatment and/or p73 knock-down in Rh30 cells |
GSE15704 |
ChIP-on-Chip data from Rh30 cells +/- rapamycin treatment |
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Relations |
BioProject |
PRJNA116611 |
Supplementary file |
Size |
Download |
File type/resource |
GSE15719_RAW.tar |
1.1 Gb |
(http)(custom) |
TAR (of BAR, CEL) |
Raw data provided as supplementary file |
Processed data included within Sample table |
Processed data provided as supplementary file |
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