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| Status |
Public on Jan 27, 2021 |
| Title |
Expression data of Tfe3/Tfeb- or GFP-knocked-down RAW264 macrophages treated with or without iron |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
In an attempt to elucidate the role of MiT/TFE families in the iron-mediated phenotypic changes of macrophages, we performed DNA microarray analysis using ferric chloride-stimulated RAW264 cells transfected with Tfe3/Tfeb or GFP.
A number of genes upregulated by ferric chloride treatment in siGFP-transfected RAW264 cells were decreased in siTfe3/Tfeb-transfected cells, suggesting MiT/TFE families are involved in phenotypic changes of macrophages induced by iron.
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| Overall design |
RAW264 macrophages transfected with or without siTfe3/Tfeb were stimulated with or without ferric chloride for 24 h. Microarray analysis was performed using SurePrint G3 Mouse 8x60K ver. 2 .0.
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| Contributor(s) |
Kanamori Y, Tanaka M, Suganami T |
| Citation(s) |
33521599 |
|
https://doi.org/10.1016/j.isci.2020.102032
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| Submission date |
Sep 04, 2020 |
| Last update date |
Feb 08, 2021 |
| Contact name |
Yohei Kanamori |
| E-mail(s) |
kanamori@riem.nagoya-u.ac.jp
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| Organization name |
Nagoya University
|
| Street address |
Furo-cho, Chikusa-ku
|
| City |
Nagoya |
| ZIP/Postal code |
464-8601 |
| Country |
Japan |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA661447 |
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