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Series GSE160118 Query DataSets for GSE160118
Status Public on Nov 27, 2021
Title Minimal Genomic Instability and Increased Immune Activity Differentiate EBV-positive PTCL from ENKTL and PTCL NOS [CNA]
Organism Homo sapiens
Experiment type Genome variation profiling by array
Summary The molecular biology of the primary nodal EBV-positive variant of PTCL (PTCL-EBV) and its relationship with extranodal NK/T-cell lymphoma (ENKTL) and peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) remains poorly understood.
In this study, we assessed the relationship between the three diseases using gene and EBV miRNA expression profiling, and copy number aberration (CNA) analyses and attempted to characterize the degree of genomic instability (GI). This series is the oncoscan CNA data of 77 NKTL samples.
 
Overall design We used a combinational approach involving gene expression profiling (GEP), copy number alterations (CNA) analyses and EBV miRNA expression profiling in a large cohort of adult patients
Web link https://pubmed.ncbi.nlm.nih.gov/35021606/
 
Contributor(s) Ng S, Chen S
Citation(s) 35021606
Submission date Oct 26, 2020
Last update date Feb 10, 2022
Contact name Siok-Bian Ng
E-mail(s) patnsb@nus.edu.sg
Organization name National University Health System, Singapore
Department Department of Pathology
Street address National University Hospital, 5 Lower Kent Ridge Road, Main Building, level 3
City Singapore
ZIP/Postal code 119074
Country Singapore
 
Platforms (2)
GPL18602 [OncoScan] Affymetrix OncoScan FFPE Assay
GPL21558 [OncoScan_CNV] Affymetrix OncoScan CNV FFPE Assay
Samples (77)
GSM4860168 extranodal NKTL,NKTL53,FFPE Preparation
GSM4860169 extranodal NKTL,NKTL23A,FFPE Preparation
GSM4860170 EBV+ PTCL (nodal TNKL),NKTL40,FFPE Preparation
This SubSeries is part of SuperSeries:
GSE160120 Minimal Genomic Instability and Increased Immune Activity Differentiate EBV-positive PTCL from ENKTL and PTCL NOS
Relations
BioProject PRJNA672043

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE160118_CNA_oncoscan_data_processed_Matrix.txt.gz 151.0 Kb (ftp)(http) TXT
GSE160118_RAW.tar 672.1 Mb (http)(custom) TAR (of CEL)
Processed data are available on Series record

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