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Status |
Public on Sep 22, 2021 |
Title |
Dual RNA-seq transcriptome analysis of chicken caeca infected with Eimeria tenella |
Organism |
Gallus gallus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
In order to elucidate the infection mechanisms of Eimeria tenella and the chicken immune response, chickens were infected with Eimeria tenella strain Hougton sporozoites. Samples were taken at 0, 1, 2, 3, 4 and 10 days post-infection and mRNA sequenced. A dual-RNA seq analysis was carried out, comparing the expression of infected chickens during each sampling time point with uninfected chickens and comparing E. tenella samples during the infection with a sample of pure sporozoites. The results show a variety of response signals in the chicken, both previously known and unknown, as well as a clear role for a variety of infection-related genes in E. tenella
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Overall design |
mRNA profiles of chicken caeca, both uninfected and infected with Eimeria tenella sporozoites
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Contributor(s) |
Sandholt AK, Wattrang E, Lilja T, Ahola H, Lundén A, Troell KG, Svärd S, Söderlund R |
Citation(s) |
34521339 |
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Submission date |
Oct 26, 2020 |
Last update date |
Sep 22, 2021 |
Contact name |
Arnar Kari Sigurdarson Sandholt |
E-mail(s) |
a.k.sigurdarsonsandholt@uu.nl
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Organization name |
Utrecht University
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Department |
IRAS
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Street address |
Yalelaan 2
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City |
Utrecht |
ZIP/Postal code |
3584 CM |
Country |
Netherlands |
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Platforms (1) |
GPL26853 |
Illumina NovaSeq 6000 (Gallus gallus) |
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Samples (36)
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Relations |
BioProject |
PRJNA672156 |
SRA |
SRP288913 |