|
| Status |
Public on Feb 01, 2010 |
| Title |
Aortic gene expression profile of rats exposed in utero to maternal diabetes |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
Epidemiologic studies have clearly identified modifications of fetal environment as a risk factor for the development of cardiovascular diseases and of metabolic syndrome in adulthood. In our experimental model, rats exposed to maternal diabetes develop a volume-dependent hypertension as early as 6 month of age. In order to determine if the development of hypertension results from an abnormal vascular fetal programming, gene expression profile of thoracic aorta were studied in adult rats exposed in utero to maternal hyperglycemia.
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| |
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| Overall design |
10 samples total (including 5 dye swaps)
|
| |
|
| Contributor(s) |
FASSOT-LUCHT C, Barbry P, Lebrigand K |
| Citation(s) |
20622163 |
| |
| Submission date |
Jun 23, 2009 |
| Last update date |
Oct 16, 2015 |
| Contact name |
Celine Fassot-Lucht |
| E-mail(s) |
celine.fassot@inserm.fr
|
| Organization name |
INSERM U1083
|
| Department |
BNMI
|
| Street address |
Rue Haute de Reculée
|
| City |
Angers |
| ZIP/Postal code |
49045 cedex 01 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL890 |
Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version) |
|
| Samples (9)
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| Relations |
| BioProject |
PRJNA117453 |
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