|
| Status |
Public on Mar 15, 2021 |
| Title |
Transcriptome profile of tra1 mutant in S. cerevisiae |
| Organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Tra1 is an essential component of the SAGA and NuA4 transcriptional co-activator complexes and is linked to multiple cellular processes associated with the yeast response to antifungal drugs. This submission contains RNA sequencing data from Saccharomyces cerevisiae strains expressing a Tra1 mutant with three arginine to glutamine mutations in the PI3K domain (tra1Q3; Berg et al., 2018). Our goal was to identify how gene expression changes due to mutation to the PI3K domain of Tra1.
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| |
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| Overall design |
mRNA of strains expressing tra1Q3 compared to strains expressing wild type TRA1
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| |
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| Contributor(s) |
Razzaq I, Berg MD, Jiang Y, Genereaux J, Uthayakumar D, Kim GH, Brandl CJ, Lajoie P, Shapiro RS |
| Citation(s) |
34849885 |
| Submission date |
Mar 15, 2021 |
| Last update date |
May 01, 2022 |
| Contact name |
Matthew Berg |
| E-mail(s) |
mberg2@uwo.ca
|
| Organization name |
University of Western Ontario
|
| Department |
Biochemistry
|
| Street address |
1151 Richmond St
|
| City |
London |
| State/province |
Ontario |
| ZIP/Postal code |
N6A5C1 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL13821 |
Illumina HiSeq 2000 (Saccharomyces cerevisiae) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA714657 |
| SRA |
SRP310730 |
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