Methylation profiling by high throughput sequencing
Summary
Senescence is altered in mutants that are defective in DNA methylation; in leaves the process of senescence is associated with very moderate initial decline in chromosomal methylation that reversed at later stages. Methylation changes were not specifically associated with senescence-associated genes and potential regulation of transcription factor binding is suggested.
Overall design
Examination of cytosine methylation at four distinct timepoints after flower induction in A. thaliana
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