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| Status |
Public on Jul 01, 2021 |
| Title |
Differentially expressed genes in CSRP2BP knockdown HTR-8 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
CSRP2BP plays an important role in cell cycle progression, apoptosis and mammalian development, CSRP2BP knockdown by specific shRNA (CSRP2BP-shRNA) significantly inhibited the proliferation, migration, and invasion of HTR-8 trophoblast cells, and placental explant outgrowth, while CSRP2BP overexpression did the opposite. To elucidate the mechanisms by which CSRP2BP regulated the function of trophoblast cells, we performed microarray analysis to compare the transcription profiling between the HTR-8-shNC and HTR-8-shCSRP2BP cells
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| Overall design |
Microarray analysis analysis was performed using 3 independent replicates. HTR8_shcon is control group, HTR8_shBP is experimental group
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| Contributor(s) |
Wei Y, Wang Z, Ma Y, Li Q |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 30, 2021 |
| Last update date |
Jul 02, 2021 |
| Contact name |
Chonghui Hu |
| E-mail(s) |
huchonghui@gdph.org.cn
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| Organization name |
Guangdong Provincial People's Hospital
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| Department |
Department of General Surgery
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| Street address |
106 Zhongshan Er Road
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| City |
Guangzhou |
| State/province |
Guangdong |
| ZIP/Postal code |
510080 |
| Country |
China |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA742652 |
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