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| Status |
Public on Jul 17, 2022 |
| Title |
Role of YAP/TAZ-TEAD in human trophoblast |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
During placentation, placental cytotrophoblast cells differentiate into syncytiotrophoblast cells and extravillous trophoblast cells. In placenta, the expression of various genes is regulated by the Hippo pathway through the transcriptional coactivator YAP/TAZ-TEAD activity. To examine the effect of YAP/TAZ and/or TEAD on trophoblast differentiation, knockdown experiments were performed.
Microarray analysis were performed to identify YAP/TAZ and/or TEAD target genes in human trophoblast.
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| Overall design |
Observation of gene expression changes in human trophoblast stem cells after treatmet with siRNAs targeting YAP/TAZ or TEAD using microarray.
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| Contributor(s) |
Mizutani T |
| Citation(s) |
35993908 |
| Submission date |
Aug 27, 2021 |
| Last update date |
Nov 04, 2022 |
| Contact name |
Tetsuya Mizutani |
| E-mail(s) |
mizutani237@gmail.com
|
| Organization name |
Fukui Prefectural University
|
| Street address |
4-1-1 Kenjojima
|
| City |
Eiheiji |
| State/province |
Fukui |
| ZIP/Postal code |
910-1195 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA758260 |
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