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| Status |
Public on Nov 23, 2021 |
| Title |
CDC-like Kinase 4 Deficiency Contributes to Pathological Cardiac Hypertrophy by Modulating NEXN Phosphorylation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To investigate how sustained NEXN phosphorylation ameliorated the pathological phenotype in Clk4-cKO mice. We performed microarray analysis in the Clk4-cKO myocardium treated with AAV NEXN-S437E, wherein AAV NEXN-WT served as a control.
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| Overall design |
Clk4-cKO myocardium treated with AAV NEXN-S437E, wherein AAV NEXN-WT served as a control. n = 3 animals for each group.
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| Contributor(s) |
Huang J, Chen Y |
| Citation(s) |
35907876 |
| |
| Submission date |
Nov 07, 2021 |
| Last update date |
Aug 16, 2022 |
| Contact name |
Jian Huang |
| E-mail(s) |
huang_jian126@tongji.edu.cn
|
| Organization name |
Shanghai East Hospital, Tongji University School of Medicine
|
| Department |
Department of Cardiology
|
| Street address |
No. 150 Jimo Road
|
| City |
Shanghai |
| ZIP/Postal code |
200120 |
| Country |
China |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA782453 |
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