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Status |
Public on Nov 23, 2021 |
Title |
CDC-like Kinase 4 Deficiency Contributes to Pathological Cardiac Hypertrophy by Modulating NEXN Phosphorylation |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
To investigate how sustained NEXN phosphorylation ameliorated the pathological phenotype in Clk4-cKO mice. We performed microarray analysis in the Clk4-cKO myocardium treated with AAV NEXN-S437E, wherein AAV NEXN-WT served as a control.
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Overall design |
Clk4-cKO myocardium treated with AAV NEXN-S437E, wherein AAV NEXN-WT served as a control. n = 3 animals for each group.
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Contributor(s) |
Huang J, Chen Y |
Citation(s) |
35907876 |
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Submission date |
Nov 07, 2021 |
Last update date |
Aug 16, 2022 |
Contact name |
Jian Huang |
E-mail(s) |
huang_jian126@tongji.edu.cn
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Organization name |
Shanghai East Hospital, Tongji University School of Medicine
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Department |
Department of Cardiology
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Street address |
No. 150 Jimo Road
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City |
Shanghai |
ZIP/Postal code |
200120 |
Country |
China |
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Platforms (1) |
GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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Samples (6)
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Relations |
BioProject |
PRJNA782453 |