|
Status |
Public on Oct 11, 2023 |
Title |
miR-214-3p overexpression inhibits apoptotsis during induction of breast cancer |
Organism |
Equus caballus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We treated horse mammary derived epithelial cells (MDECs) with either a miR-214-3p mimic or a negative mimic control in the presence of the carcinogenic agent DMBA. Over expression of miR-214-3p suppressed cell apoptosis compared to the control, and suggests a potential oncogenic role in breast cancer.
|
|
|
Overall design |
Treatment of horse mammary derived epithelial cell cultures with miR-214 mimic or negative mimic control and DMBA followed by RNAseq.
|
|
|
Contributor(s) |
Van de Walle G, Sethupathy P, Kanke M |
Citation(s) |
37789172 |
|
Submission date |
Nov 30, 2021 |
Last update date |
Oct 11, 2023 |
Contact name |
Praveen Sethupathy |
Organization name |
Cornell University
|
Lab |
Dr. Sethupathy Lab
|
Street address |
Cornell University College of Veterinary Medicine, Box 17
|
City |
Ithica |
State/province |
NY |
ZIP/Postal code |
14853 |
Country |
USA |
|
|
Platforms (1) |
GPL21941 |
Illumina HiSeq 2500 (Equus caballus) |
|
Samples (6)
|
|
Relations |
BioProject |
PRJNA784942 |
SRA |
SRP348657 |