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Series GSE189879 Query DataSets for GSE189879
Status Public on Oct 11, 2023
Title miR-214-3p overexpression inhibits apoptotsis during induction of breast cancer
Organism Equus caballus
Experiment type Expression profiling by high throughput sequencing
Summary We treated horse mammary derived epithelial cells (MDECs) with either a miR-214-3p mimic or a negative mimic control in the presence of the carcinogenic agent DMBA. Over expression of miR-214-3p suppressed cell apoptosis compared to the control, and suggests a potential oncogenic role in breast cancer.
 
Overall design Treatment of horse mammary derived epithelial cell cultures with miR-214 mimic or negative mimic control and DMBA followed by RNAseq.
 
Contributor(s) Van de Walle G, Sethupathy P, Kanke M
Citation(s) 37789172
Submission date Nov 30, 2021
Last update date Oct 11, 2023
Contact name Praveen Sethupathy
Organization name Cornell University
Lab Dr. Sethupathy Lab
Street address Cornell University College of Veterinary Medicine, Box 17
City Ithica
State/province NY
ZIP/Postal code 14853
Country USA
 
Platforms (1)
GPL21941 Illumina HiSeq 2500 (Equus caballus)
Samples (6)
GSM5708934 MDECs, miR-214 mimic #1
GSM5708935 MDECs, negative mimic control#1
GSM5708936 MDECs, miR-214 mimic #2
Relations
BioProject PRJNA784942
SRA SRP348657

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Supplementary file Size Download File type/resource
GSE189879_DESeq_MDEC_normalized_counts.csv.gz 957.1 Kb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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