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Status |
Public on Apr 05, 2022 |
Title |
rDNA Array Length is a Major Determinant of Replicative Lifespan in Budding Yeast - ATACseq |
Organism |
Saccharomyces cerevisiae |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
In this study we perform ATAC-seq of budding yeast strains with variable copy number of the rRNA genes (rDNA CN). We aim to better understand the relationship between DNA accessibility and replicative lifespan in strains with variable rDNA CN.
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Overall design |
Examination of ATAC-seq profile of strains with variable rDNA array lengths.
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Contributor(s) |
Hotz M, Thayer NH, Hendrickson DG, Schinski EL, Xu J, Gottschling DE |
Citation(s) |
35394872 |
Submission date |
Jan 13, 2022 |
Last update date |
Jul 05, 2022 |
Contact name |
Nathaniel H Thayer |
E-mail(s) |
nate@calicolabs.com
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Organization name |
Calico Life Sciences LLC
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Street address |
1130 Veteran's Blvd
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City |
South San Francisco |
State/province |
CA |
ZIP/Postal code |
94080 |
Country |
USA |
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Platforms (1) |
GPL27812 |
Illumina NovaSeq 6000 (Saccharomyces cerevisiae) |
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Samples (12)
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GSM5814857 |
ATACseq profile from strain with 72 rDNA repeats [CLS_rDNAcn_ATAC_strain49] |
GSM5814858 |
ATACseq profile from strain with 129 rDNA repeats [CLS_rDNAcn_ATAC_strain48] |
GSM5814859 |
ATACseq profile from strain with 197 rDNA repeats [CLS_rDNAcn_ATAC_strain87] |
GSM5814860 |
ATACseq profile from strain with 208 rDNA repeats [CLS_rDNAcn_ATAC_strain86] |
GSM5814861 |
ATACseq profile from strain with 104 rDNA repeats [CLS_rDNAcn_ATAC_strain50] |
GSM5814862 |
ATACseq profile from strain with 118 rDNA repeats [CLS_rDNAcn_ATAC_strain25] |
GSM5814863 |
ATACseq profile from strain with 162 rDNA repeats [CLS_rDNAcn_ATAC_strain90] |
GSM5814864 |
ATACseq profile from strain with 237 rDNA repeats [CLS_rDNAcn_ATAC_strain34] |
GSM5814865 |
ATACseq profile from strain with 84 rDNA repeats [CLS_rDNAcn_ATAC_strain105] |
GSM5814866 |
ATACseq profile from strain with 147 rDNA repeats [CLS_rDNAcn_ATAC_strain29] |
GSM5814867 |
ATACseq profile from strain with 156 rDNA repeats [CLS_rDNAcn_ATAC_strain42] |
GSM5814868 |
ATACseq profile from strain with 225 rDNA repeats [CLS_rDNAcn_ATAC_strain89] |
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This SubSeries is part of SuperSeries: |
GSE193600 |
rDNA Array Length is a Major Determinant of Replicative Lifespan in Budding Yeast. |
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Relations |
BioProject |
PRJNA796838 |