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Series GSE198901 Query DataSets for GSE198901
Status Public on Oct 16, 2023
Title Single-cell transcriptome profiling of mouse cardio-pharyngeal development under maternal diabetes mellitus
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We employed single cell RNA sequencing to interrogate the consequence of maternal diabetes in cardiac and craniopharyngeal development
 
Overall design Examination of single cell RNA sequnecing from craniopharyngeal and cardiac cells captured at E10.5 fetues from vehicle pre-treated or streptozoticine pre-treated females. At least 3 biological replicate embryos were analyzed per genotype.
 
Contributor(s) Nishino T, Pelonero A, Srivastava D
Citation(s) 39183978
Tomohiro Nishino, Sanjeev S Ranade, Angelo Pelonero, Benjamin J van Soldt, Lin Ye, Michael Alexanian, Frances Koback, Yu Huang, Langley Grace Wallace, Nandhini Sadagopan, Adrienne Lam, Lyandysha V Zholudeva, Feiya Li, Arun Padmanabhan, Reuben Thomas, Joke G van Bemmel, Casey A Gifford, Mauro W Costa, and Deepak Srivastava. Single-cell multimodal analyses reveal epigenomic and transcriptomic basis for birth defects in maternal diabetes. Nat Cardiovasc Res 2, 1190-1203 (2023). doi:10 1038/s44161-023-00367-y
Submission date Mar 17, 2022
Last update date Sep 27, 2024
Contact name Tomohiro Nishino
E-mail(s) tomo.nishino@gladstone.ucsf.edu
Organization name Gladstone Institutes (UCSF)
Department Cardiovascular Disease Institute
Lab Srivastava Lab
Street address 1650 Owens Street
City San Francisco
State/province California
ZIP/Postal code 94158
Country USA
 
Platforms (2)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (6)
GSM5959194 E105_Veh_01 RNA-seq
GSM5959195 E105_Veh_02 RNA-seq
GSM5959196 E105_Veh_03 RNA-seq
This SubSeries is part of SuperSeries:
GSE198905 Single-cell profiling of mouse cardio-pharyngeal development under maternal diabetes mellitus
Relations
BioProject PRJNA817268

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Supplementary file Size Download File type/resource
GSE198901_barcodes.tsv.gz 221.8 Kb (ftp)(http) TSV
GSE198901_features.tsv.gz 254.1 Kb (ftp)(http) TSV
GSE198901_matrix.mtx.gz 709.3 Mb (ftp)(http) MTX
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Raw data are available in SRA
Processed data are available on Series record

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