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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Dec 22, 2023 |
| Title |
Single-Cell RNA Sequencing Reveals Metabolic Stress-Dependent Activation of Cardiac Macrophages in a Model of Dyslipidemia-Induced Diastolic Dysfunction |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062984
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jul 22, 2022 |
| Last update date |
Jan 16, 2024 |
| Contact name |
Paolo Kunderfranco |
| E-mail(s) |
Paolo.Kunderfranco@humanitasresearch.it
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| Organization name |
Humanitas Research Hospital
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| Department |
Research
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| Lab |
Bioinformatic Unit
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| Street address |
Via Rita Levi Montalcini 4
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| City |
Pieve Emanuele |
| State/province |
Milano |
| ZIP/Postal code |
20090 |
| Country |
Italy |
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| Platforms (3) |
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| Samples (36)
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| GSM6346243 |
WT_HFD_b, replicate 2,scRNAseq |
| GSM6346244 |
ApoE_KO_CD_a, replicate 1,scRNAseq |
| GSM6346245 |
ApoE_KO_CD_b, replicate 2,scRNAseq |
| GSM6346246 |
ApoE_KO_HFD_a, replicate 1,scRNAseq |
| GSM6346247 |
ApoE_KO_HFD_b, replicate 2,scRNAseq |
| GSM6376729 |
Wt CD, replicate 1 |
| GSM6376730 |
Wt CD, replicate 2 |
| GSM6376731 |
Wt CD, replicate 3 |
| GSM6376732 |
Wt HFD, replicate 1 |
| GSM6376733 |
Wt HFD, replicate 2 |
| GSM6376734 |
Wt HFD, replicate 3 |
| GSM6376735 |
ApoE KO CD, replicate 1 |
| GSM6376736 |
ApoE KO CD, replicate 2 |
| GSM6376737 |
ApoE KO CD, replicate 3 |
| GSM6376738 |
ApoE KO HFD, replicate 1 |
| GSM6376739 |
ApoE KO HFD, replicate 2 |
| GSM6376740 |
ApoE KO HFD, replicate 3 |
| GSM7596255 |
Ccr2+ vehicle CD 1 |
| GSM7596256 |
Ccr2+ vehicle CD 2 |
| GSM7596257 |
Ccr2+ Dapa CD 1 |
| GSM7596258 |
Ccr2+ Dapa CD 2 |
| GSM7596259 |
Ccr2+ vehicle HFD 1 |
| GSM7596260 |
Ccr2+ vehicle HFD 2 |
| GSM7596261 |
Ccr2+ Dapa HFD 1 |
| GSM7596262 |
Ccr2+ Dapa HFD 2 |
| GSM7596263 |
Ccr2- vehicle CD 1 |
| GSM7596264 |
Ccr2- vehicle CD 2 |
| GSM7596265 |
Ccr2- Dapa CD 1 |
| GSM7596266 |
Ccr2- Dapa CD 2 |
| GSM7596267 |
Ccr2- vehicle HFD 1 |
| GSM7596268 |
Ccr2- vehicle HFD 2 |
| GSM7596269 |
Ccr2- Dapa HFD 1 |
| GSM7596270 |
Ccr2- Dapa HFD 2 |
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| This SuperSeries is composed of the following SubSeries: |
| GSE208425 |
An inflammatory single-cell RNA sequencing signature driven by metabolic stress in a new mouse model of heart failure with preserved ejection fraction and its reversion by the SGLT2 inhibitor dapagliflozin [scRNA-Seq cd45+] |
| GSE209548 |
An inflammatory single-cell RNA sequencing signature driven by metabolic stress in a new mouse model of heart failure with preserved ejection fraction and its reversion by the SGLT2 inhibitor dapagliflozin [RNA-seq cardiomyocytes] |
| GSE237156 |
An inflammatory single-cell RNA sequencing signature driven by metabolic stress in a new mouse model of heart failure with preserved ejection fraction and its reversion by the SGLT2 inhibitor dapagliflozin [RNA-Seq macrophages] |
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| Relations |
| BioProject |
PRJNA861248 |
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