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Status |
Public on Oct 06, 2010 |
Title |
Neuroinflammation in Advanced Canine Glaucoma |
Organism |
Canis lupus familiaris |
Experiment type |
Expression profiling by array
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Summary |
Dogs frequently develop glaucoma, a disease that leads to vision loss due to loss of retinal ganglion cells and degeneration of axons within the optic nerve. We used Affymetrix Gene chips to characterize transcriptional changes between healthy and glaucomatous retinas.
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Overall design |
These data describe gene expression changes in the canine retina with glaucoma. RNA was isolated from the retinas of 5 dogs with advanced glaucoma and from 5 normal individuals.
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Contributor(s) |
Grozdanic SG, Kuehn MH, Kardon RH, Harper MM, Adamus G, Jiang B, Kecova H |
Citation(s) |
21042562 |
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Submission date |
May 17, 2010 |
Last update date |
Mar 22, 2012 |
Contact name |
Markus H Kuehn |
Organization name |
University of Iowa
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Department |
Ophthalmology and Visual Sciences
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Street address |
375 Newton Road
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City |
Iowa City |
State/province |
IA |
ZIP/Postal code |
52242 |
Country |
USA |
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Platforms (1) |
GPL3738 |
[Canine_2] Affymetrix Canine Genome 2.0 Array |
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Samples (10)
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GSM544026 |
canine retina, glaucoma, biol. rep1 |
GSM544027 |
canine retina, glaucoma, biol. rep2 |
GSM544028 |
canine retina, glaucoma, biol. rep3 |
GSM544029 |
canine retina, glaucoma, biol. rep4 |
GSM544030 |
canine retina, glaucoma, biol. rep5 |
GSM544031 |
canine retina, healthy, biol. rep1 |
GSM544032 |
canine retina, healthy, biol. rep2 |
GSM544033 |
canine retina, healthy, biol. rep3 |
GSM544034 |
canine retina, healthy, biol. rep4 |
GSM544035 |
canine retina, healthy, biol. rep5 |
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Relations |
BioProject |
PRJNA126845 |
Supplementary file |
Size |
Download |
File type/resource |
GSE21879_RAW.tar |
35.3 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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