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Series GSE218873 Query DataSets for GSE218873
Status Public on Nov 08, 2023
Title Features and protective efficacy of human monoclonal antibodies targeting M. tuberculosis arabinomannan
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Protein profiling by protein array
Summary Human antibody responses to AM/LAM are heterogenous and knowledge of reactivity to specific glycan epitopes at the monoclonal level is limited.
Using novel glycan arrays, we characterized a very high affinity monoclonal antibody P1AM25 to AM/LAM, determined this mAb recognized distinct glycan epitopes from other anti-AM/LAM mAbs reported.
Overall design Monoclonal antibodies at 5 ug/ml were tested for direct binding to 61 synthetic oligosaccharides
Contributor(s) Liu Y, Chen T, Lowary TL, Achkar JM
Citation(s) 37733444
Submission date Nov 28, 2022
Last update date Nov 09, 2023
Contact name Jacqueline M. Achkar
Organization name Albert Einstein College of Medicine
Street address 1300 Morris Park Avenue
City Bronx
ZIP/Postal code 10461
Country USA
Platforms (1)
GPL32887 LAM Antigens Array
Samples (2)
GSM6758069 P1AM25 [Subarray 30]
GSM6758091 P1AM25 [Subarray 61]
BioProject PRJNA906063

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE218873_LAM30array_sample_OS_location.xlsx 11.8 Kb (ftp)(http) XLSX
GSE218873_RAW.tar 270.0 Kb (http)(custom) TAR (of GPR, TXT)
Processed data provided as supplementary file

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