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| Status |
Public on Feb 10, 2023 |
| Title |
Changes in miRNA expression during infection with strong IBDV strains |
| Organism |
Gallus gallus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
In our previous studies, we found that the bursae of Fabricius in chickens infected with IBDV were severely atrophied and resulted in immune suppression in the chickens. Therefore, we decided to detect the differential expression of miRNA in chickens infected with IBDV by RNA-seq. We then used the data obtained from bursa of Fabricius RNA-seq for gene expression profiling. Our ultimate goal is to study the regulatory mechanisms of host mirnas on IBDV viruses or cells.
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| Overall design |
Comparative miRNA expression profiling analysis of miRNA-seq data for bursa of Fabricius.
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| Contributor(s) |
Chen Z, Leng M, Chen F, Lin W |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 31, 2023 |
| Last update date |
Feb 10, 2023 |
| Contact name |
Zixian Chen |
| E-mail(s) |
chanchiyin96@stu.scau.edu.cn
|
| Organization name |
South China Agriculture University
|
| Street address |
Wushan Road No.483
|
| City |
Guangzhou |
| ZIP/Postal code |
510642 |
| Country |
China |
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| Platforms (1) |
| GPL26853 |
Illumina NovaSeq 6000 (Gallus gallus) |
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| Samples (2) |
| GSM7012528 |
bursa of Fabricius, Normal control, 3 day, rep1 |
| GSM7012529 |
bursa of Fabricius, IBDV-infected, 3 day, rep1 |
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| Relations |
| BioProject |
PRJNA929941 |
