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| Status |
Public on Sep 12, 2023 |
| Title |
Investigating the expression signatures of circRNA in pulmonary arteial hypertension |
| Organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
To investigate the underlying mechanism of pulmonary hypertension, the model of hypoxia-treated pulmonary arterial hypertension (PAH) rats were constructed to detect the differentially expressed profile of circRNAs in lung tissue of PAH rat. The whole genome microarray expression profiling analysis as a discovery platform have been employed to identify genes difference.
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| Overall design |
The male rats were exposed to hypoxia (10% oxygen) in a ventilated chamber to induce pulmonary arterial hypertension model, and control rats were exposed to normoxic condition. After 3 weeks late, the lung tissue was collected to detect the circRNA expression profile.
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| Contributor(s) |
Sun L, Zhang T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 08, 2023 |
| Last update date |
Sep 13, 2023 |
| Contact name |
Tiantai Zhang |
| E-mail(s) |
ttzhang@imm.ac.cn
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| Organization name |
Chinese Academy of Medical Sciences & Peking Union Medical College
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| Department |
Institute of Materia Medica
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| Street address |
No. 1, Xiannongtan Street
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| City |
Beijing |
| State/province |
Beijing |
| ZIP/Postal code |
100050 |
| Country |
China |
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| Platforms (1) |
| GPL21828 |
082778 Arraystar Rat CircRNA microarray V1 |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA942308 |
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