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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Oct 19, 2023 |
| Title |
SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Other
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00358-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1934590923003582%3Fshowall%3Dtrue
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| Citation(s) |
37863054 |
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| Submission date |
Apr 20, 2023 |
| Last update date |
Jan 18, 2024 |
| Contact name |
Margaret Goodell |
| E-mail(s) |
goodell@bcm.edu
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| Phone |
7137921265
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| Organization name |
Baylor College of Medicine
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| Street address |
1 Baylor Plz, Rm N1030
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| City |
HOUSTON |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
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| Platforms (1) |
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| Samples (62)
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| GSM7179160 |
ATAC, HSPC, WT, NT, rep 1 |
| GSM7179161 |
ATAC, HSPC, WT, NT, rep 2 |
| GSM7179162 |
ATAC, HSPC, Mut, NT, rep 1 |
| GSM7179163 |
ATAC, HSPC, Mut, NT, rep 2 |
| GSM7179164 |
ATAC, HSPC, WT, Trx, rep 1 |
| GSM7179165 |
ATAC, HSPC, WT, Trx, rep 2 |
| GSM7179166 |
ATAC, HSPC, WT, Trx, rep 3 |
| GSM7179167 |
ATAC, HSPC, Mut, Trx, rep 1 |
| GSM7179168 |
ATAC, HSPC, Mut, Trx, rep 2 |
| GSM7179169 |
ATAC, HSPC, Mut, Trx, rep 3 |
| GSM7179208 |
CaR, HSPC, WT, NT, H3K27me3 |
| GSM7179209 |
CaR, HSPC, Mut, NT, H3K27me3 |
| GSM7179210 |
CaR, HSPC, WT, NT, mIgG |
| GSM7179211 |
CaR, HSPC, Mut, NT, mIgG |
| GSM7179212 |
CaR, HSPC, WT, NT, H2AZ, rep1 |
| GSM7179213 |
CaR, HSPC, WT, NT, H2AZ, rep2 |
| GSM7179214 |
CaR, HSPC, Mut, NT, H2AZ, rep1 |
| GSM7179215 |
CaR, HSPC, Mut, NT, H2AZ, rep2 |
| GSM7179216 |
CaR, HSPC, WT, NT, SRCAP, rep1 |
| GSM7179217 |
CaR, HSPC, WT, NT, SRCAP, rep2 |
| GSM7179218 |
CaR, HSPC, Mut, NT, SRCAP, rep1 |
| GSM7179219 |
CaR, HSPC, Mut, NT, SRCAP, rep2 |
| GSM7179220 |
CaR, HSPC, WT, Trx, H3K27me3 |
| GSM7179221 |
CaR, HSPC, Mut, Trx, H3K27me3 |
| GSM7179222 |
CaR, HSPC, WT, Trx, mIgG |
| GSM7179223 |
CaR, HSPC, Mut, Trx, mIgG |
| GSM7179224 |
CaR, HSPC, WT, Trx, H2AZ, rep1 |
| GSM7179225 |
CaR, HSPC, WT, Trx, H2AZ, rep2 |
| GSM7179226 |
CaR, HSPC, Mut, Trx, H2AZ, rep1 |
| GSM7179227 |
CaR, HSPC, Mut, Trx, H2AZ, rep2 |
| GSM7179228 |
CaR, HSPC, WT, Trx, SRCAP, rep1 |
| GSM7179229 |
CaR, HSPC, WT, Trx, SRCAP, rep2 |
| GSM7179230 |
CaR, HSPC, Mut, Trx, SRCAP, rep1 |
| GSM7179231 |
CaR, HSPC, Mut, Trx, SRCAP, rep2 |
| GSM7179232 |
Isolated HSPCs, Germline, no treatment_1 WT |
| GSM7179233 |
Isolated HSPCs, Germline, no treatment_2 WT |
| GSM7179234 |
Isolated HSPCs, Germline, no treatment_1 Srcap mutant |
| GSM7179235 |
Isolated HSPCs, Germline, no treatment_2 Srcap mutant |
| GSM7179236 |
Isolated HSPCs, Transplantation, 20-weeks_1 WT |
| GSM7179237 |
Isolated HSPCs, Transplantation, 20-weeks_2 WT |
| GSM7179238 |
Isolated HSPCs, Transplantation, 20-weeks_1 Srcap mutant |
| GSM7179239 |
Isolated HSPCs, Transplantation, 20-weeks_2 Srcap mutant |
| GSM7179240 |
Isolated HSPCs, Transplantation, 2-weeks_1 WT |
| GSM7179241 |
Isolated HSPCs, Transplantation, 2-weeks_2 WT |
| GSM7179242 |
Isolated HSPCs, Transplantation, 2-weeks_1 Srcap mutant |
| GSM7179243 |
Isolated HSPCs, Transplantation, 2-weeks_2 Srcap mutant |
| GSM7179244 |
Isolated HSPCs, Doxorubicin IP, 12-hours_1 WT |
| GSM7179245 |
Isolated HSPCs, Doxorubicin IP, 12-hours_2 WT |
| GSM7179246 |
Isolated HSPCs, Doxorubicin IP, 12-hours_1 Srcap mutant |
| GSM7179247 |
Isolated HSPCs, Doxorubicin IP, 12-hours_2 Srcap mutant |
| GSM7179248 |
Isolated B cells, Transplantation, 2-weeks_1 WT |
| GSM7179249 |
Isolated B cells, Transplantation, 2-weeks_2 WT |
| GSM7179250 |
Isolated B cells, Transplantation, 2-weeks_1 Srcap mutant |
| GSM7179251 |
Isolated B cells, Transplantation, 2-weeks_2 Srcap mutant |
| GSM7179252 |
Isolated T cells, Transplantation, 2-weeks_1 WT |
| GSM7179253 |
Isolated T cells, Transplantation, 2-weeks_2 WT |
| GSM7179254 |
Isolated T cells, Transplantation, 2-weeks_1 Srcap mutant |
| GSM7179255 |
Isolated T cells, Transplantation, 2-weeks_2 Srcap mutant |
| GSM7188416 |
Trx_20wk_WT, rep 1, scRNAseq |
| GSM7188417 |
Trx_20wk_WT, rep 2, scRNAseq |
| GSM7188418 |
Trx_20wk_Mut, rep 1, scRNAseq |
| GSM7188419 |
Trx_20wk_Mut, rep 2, scRNAseq |
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| This SuperSeries is composed of the following SubSeries:
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| GSE229862 |
SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [ATAC-Seq] |
| GSE229864 |
SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [Cut & Run] |
| GSE229865 |
SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [RNA-seq] |
| GSE230153 |
SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [scRNA-Seq] |
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| Relations |
| BioProject |
PRJNA957753 |
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