|
| Status |
Public on Nov 28, 2023 |
| Title |
Single nucleus RNA-seq of the rhesus macaque nucleus accumbens after chronic morphine exposure |
| Organism |
Macaca mulatta |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Chronic morphine exposure to rhesus macaque
|
| |
|
| Overall design |
Four subjects (3 male, 1 female; mean age: 12 years, range: 9-18 years) received daily morphine treatment for 5 months (see below); four additional subjects, matched for age, weight, and sex, served as experimental controls (3 male, 1 female; mean age: 14 years, range: 11-21 years). Control subjects had a history of nicotine or cocaine exposure but were drug free for ~1 year prior to tissue collection.
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| |
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| Contributor(s) |
Phan BN, Logan RW, Pfenning AR, Fenster RJ, Ressler KJ, Bergman J |
| Citation(s) |
38296993 |
| |
| Submission date |
May 23, 2023 |
| Last update date |
Feb 14, 2024 |
| Contact name |
BaDoi Nguyen Phan |
| E-mail(s) |
badoi.phan@pitt.edu
|
| Organization name |
Carnegie Mellon University
|
| Department |
Computational Biology
|
| Lab |
Pfenning Lab
|
| Street address |
5000 Forbes Ave
|
| City |
Pittsburgh |
| State/province |
PA |
| ZIP/Postal code |
15213 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL27943 |
Illumina NovaSeq 6000 (Macaca mulatta) |
|
| Samples (16)
|
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| This SubSeries is part of SuperSeries: |
| GSE233279 |
Single nuclei transcriptomics of human and monkey striatum implicates DNA damage, neuroinflammation, and neurodegeneration signaling in opioid use disorder |
|
| Relations |
| BioProject |
PRJNA975617 |
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