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| Status |
Public on Jul 13, 2023 |
| Title |
Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity |
| Organism |
Sus scrofa |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We performed gene expression profiling analysis using data obtained from RNA-seq of condylar cartilage cells from post-traumatic temporomandibular joint osteoarthritis model to investigate the signaling pathways critical for cellular functions during temporomandibular joint osteoarthritis pathology.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for control and osteoarthritis model in condylar cartilage cells from temporomandibular joints.
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| Contributor(s) |
Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Morel MM, Koch A, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC |
| Citation(s) |
37683603 |
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| Submission date |
Jul 10, 2023 |
| Last update date |
Oct 16, 2023 |
| Contact name |
Ikue Tosa |
| E-mail(s) |
it2318@cumc.columbia.edu
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| Organization name |
Columbia University
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| Department |
College of Dental Medicine
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| Lab |
Embree Lab
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| Street address |
P&S 16-440 630 W. 168th St.
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| City |
New York |
| State/province |
New York |
| ZIP/Postal code |
10032 |
| Country |
USA |
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| Platforms (1) |
| GPL11429 |
Illumina HiSeq 2000 (Sus scrofa) |
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| Samples (8)
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| GSM7585168 |
Control, Condylar cartilage cells, Biol rep 1 [PHCC_1] |
| GSM7585169 |
Control, Condylar cartilage cells, Biol rep 2 [PHCC_2] |
| GSM7585170 |
Control, Condylar cartilage cells, Biol rep 3 [PHCC_3] |
| GSM7585171 |
Control, Condylar cartilage cells, Biol rep 4 [PHCC_4] |
| GSM7585172 |
Osteoarthritis, Condylar cartilage cells, Biol rep 1 [PPCC_1] |
| GSM7585173 |
Osteoarthritis, Condylar cartilage cells, Biol rep 2 [PPCC_2] |
| GSM7585174 |
Osteoarthritis, Condylar cartilage cells, Biol rep 3 [PPCC_3] |
| GSM7585175 |
Osteoarthritis, Condylar cartilage cells, Biol rep 4 [PPCC_4] |
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| Relations |
| BioProject |
PRJNA993104 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE236909_00.DEGs_Out_TPM_2.xlsx |
7.4 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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