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Series GSE237561 Query DataSets for GSE237561
Status Public on Jul 17, 2024
Title Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary 126 Peripheral whole blood samples from 26 individuals across two independent cohorts were collected prior to clozapine initiation, 4-12 weeks after initiation, and a 6 months after initiation.
 
Overall design Bisulphite converted DNA from the 126 samples were hybridised to either the Illumina Infinium HumanMethylation450 BeadChip (KCL samples) or the Illumina Infinium HumanMethylationEPIC BeadChip (UMC)
 
Contributor(s) Walker EM, Gillespie A, Hannon E, McQueen G, Sendt KV, Avila A, Lally J, Egerton A, Okhuijsen-Pfeifer C, van der Horst M, Hasan A, Dempster EL, Burrage J, Bogers J, Cohen D, Boks M, Luykx J, Mill J, MacCabe J
Citation(s) 39333502
Submission date Jul 17, 2023
Last update date Oct 15, 2024
Contact name Emma Walker
E-mail(s) e.m.walker@exeter.ac.uk
Organization name University of Exeter
Street address RILD Barrack Rd
City Exeter
ZIP/Postal code EX2 5DW
Country United Kingdom
 
Platforms (2)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
GPL21145 Infinium MethylationEPIC
Samples (126)
GSM7625568 genomic DNA from ID 0003 for 'a' visit
GSM7625569 genomic DNA from ID 0003 for 'b' visit
GSM7625570 genomic DNA from ID 0003 for 'd' visit
Relations
BioProject PRJNA995741

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE237561_ProcessedData_LongitudinalClozapineNormalisedBetaMatrix.csv.gz 244.9 Mb (ftp)(http) CSV
GSE237561_RAW.tar 1.5 Gb (http)(custom) TAR (of IDAT)
Processed data are available on Series record
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