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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Dec 29, 2023 |
| Title |
An Exhausted-Like Microglial Population Accumulates in Aged and APOE4 Genotype Alzheimer’s Brains |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Other
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://www.cell.com/immunity/fulltext/S1074-7613(23)00532-0
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| Citation(s) |
38159571 |
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| Submission date |
Aug 03, 2023 |
| Last update date |
Jan 25, 2024 |
| Contact name |
Alon Millet |
| E-mail(s) |
amillet@rockefeller.edu
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| Organization name |
The Rockefeller University
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| Lab |
Tavazoie Lab
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| Street address |
1230 York Ave
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (27)
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| GSM7049627 |
E2/E3/E4 5XFAD mice, 10weeks, scRNAseq |
| GSM7049628 |
E2/E3/E4 5XFAD mice, 10weeks, HTO for demuxing |
| GSM7049629 |
E2/E3/E4 5XFAD mice, 20weeks, scRNAseq |
| GSM7049630 |
E2/E3/E4 5XFAD mice, 20weeks, HTO for demuxing |
| GSM7049631 |
E4 5XFAD mice, 60weeks, scRNAseq |
| GSM7049632 |
E4 5XFAD mice, 60weeks, scATACseq |
| GSM7049633 |
E3 5XFAD mice, 96weeks, scRNAseq |
| GSM7049634 |
E4 5XFAD mice, 96weeks, scRNAseq |
| GSM7679367 |
E2/E3/E4 5XFAD mice, 60 weeks, high and low abeta uptake, scRNAseq |
| GSM7679368 |
E2/E3/E4 5XFAD mice, 60 weeks, high and low abeta uptake, HTO for demuxing |
| GSM7679369 |
E2/E3/E4 5XFAD mice, 60 weeks, aducanumab or IgG, scRNAseq |
| GSM7679370 |
E2/E3/E4 5XFAD mice, 60 weeks, aducanumab or IgG, HTO for demuxing |
| GSM7679391 |
E2 knock-in replicate 1 |
| GSM7679392 |
E2 knock-in replicate 2 |
| GSM7679393 |
E2 knock-in replicate 3 |
| GSM7679394 |
E2 knock-in replicate 4 |
| GSM7679395 |
E2 knock-in replicate 5 |
| GSM7679396 |
E3 knock-in replicate 1 |
| GSM7679397 |
E3 knock-in replicate 2 |
| GSM7679398 |
E3 knock-in replicate 3 |
| GSM7679399 |
E3 knock-in replicate 4 |
| GSM7679400 |
E3 knock-in replicate 5 |
| GSM7679401 |
E4 knock-in replicate 1 |
| GSM7679402 |
E4 knock-in replicate 2 |
| GSM7679403 |
E4 knock-in replicate 3 |
| GSM7679404 |
E4 knock-in replicate 4 |
| GSM7679405 |
E4 knock-in replicate 5 |
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| This SuperSeries is composed of the following SubSeries:
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| GSE225503 |
scRNAseq and scATACseq of Cd45+ cells from brains of 5XFAD mice bearing distinct APOE alleles and across age |
| GSE239974 |
scRNAseq of Cd45+ cells from brains of ApoE-variant Alzheimer's mice sorted by ex-vivo amyloid beta uptake |
| GSE239975 |
scRNAseq of Cd45+ cells from brains of Aducanumab-treated ApoE-variant Alzheimer's mice |
| GSE239977 |
Bulk RNA sequencing of Cd45+ cells from brains of aged Alzheimer's mice bearing human APOE knockin |
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| Relations |
| BioProject |
PRJNA1001885 |
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