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Series GSE242358 Query DataSets for GSE242358
Status Public on Sep 30, 2023
Title MoTrPAC: Endurance Exercise Training Study In 6 Months Old Rats
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Summary MoTrPAC endurance exercise training study targets young adult (6-month-old) rats. Specifically, male and female Fischer 344 rats (n = 12) were subjected to progressive treadmill endurance exercise training for 1, 2, 4, or 8 weeks, with tissues collected 48 hours after the last exercise bout. Sex-matched sedentary, untrained rats were used as controls.
This study contributes to MoTrPAC's broader mission, which is to identify molecular changes occurring due to exercise. The ultimate goal is to understand how physical activity can improve and sustain health across various ages and fitness levels.
The program is supported by the NIH Common Fund. For additional information, visit the MoTrPAC Data Hub at https://motrpac-data.org/.

This SuperSeries is composed of the SubSeries listed below.
 
Overall design 6-month-old young adult rats (Fischer 344) were subjected to progressive endurance exercise training for 1, 2, 4, or 8 weeks, with tissues collected 48 hours after the last training bout. Sex-matched sedentary, untrained rats were used as controls. Whole blood, plasma, and 19 solid tissues were analyzed using genomics, proteomics, metabolomics, and protein immunoassay technologies, with most assays performed in a subset of these tissues. Depending on the assay, between 3 and 6 replicates per sex per time point were analyzed.
 
Citation(s) 38697122, 38693412, 38693320
BioProject PRJNA908279
Submission date Sep 05, 2023
Last update date Jun 12, 2024
Contact name Euan Ashley
Organization name Stanford University
Street address 870 Quarry Road
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
 
Platforms (1)
GPL25947 Illumina NovaSeq 6000 (Rattus norvegicus)
Samples (1747)
GSM7759762 rna-seq_blood_male_reference_1_vial_80006883006
GSM7759763 rna-seq_blood_female_reference_1_vial_80007993006
GSM7759764 rna-seq_hippoc_male_reference_2_vial_80034885205
This SuperSeries is composed of the following SubSeries:
GSE242354 MoTrPAC- Endurance Exercise Training Study In 6 Months Old Rats [RNA-seq]
GSE242355 MoTrPAC - Endurance Exercise Training Study In 6 Months Old Rats [RRBS]
GSE242357 MoTrPAC - Endurance Exercise Training Study In 6 Months Old Rats [ATAC-seq]

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE242358_RAW.tar 11.3 Gb (http)(custom) TAR (of COV)
GSE242358_README-motrpac_rat-6m-endurance_qa-qc-files.txt 13.9 Kb (ftp)(http) TXT
GSE242358_motrpac_rat-6m-endurance_phenotype_README-v5.txt 3.7 Kb (ftp)(http) TXT
GSE242358_motrpac_rat-6m-endurance_phenotype_dictionary-v5.txt.gz 6.8 Kb (ftp)(http) TXT
GSE242358_motrpac_rat-6m-endurance_phenotype_viallabel_data-v5.txt.gz 269.7 Kb (ftp)(http) TXT
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