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| Status |
Public on Sep 01, 2024 |
| Title |
PiRNA DQ571591 regulated the function of non-small cell lung cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
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| Summary |
In-depth study of the pathogenesis of NSCLC is of great significance, for the discovery of new early clinical diagnosis strategies and treatment targets for NSCLC. Epigenetics has become a research hotspot in the field of life science in recent years, and research on noncoding RNAs including PIWI-interacting RNAs (piRNAs) is an important part of this field. An increasing number of studies have shown that piRNAs play an important role in silencing transposons and regulating messenger RNA (mRNA) and long noncoding RNA (lncRNA). In the field of cancer research, piRNAs may become new molecular markers and therapeutic targets.
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| Overall design |
PiRNAs related to NSCLC were found by small noncoding RNA sequencing and qPCR detection. The target of piRNA DQ571591 was found by mRNA sequencing.
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| Contributor(s) |
Zhou L, Shi G, Feng Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 22, 2023 |
| Last update date |
Sep 01, 2024 |
| Contact name |
Chuandong Wang |
| E-mail(s) |
wangchuandong@yeah.net
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| Organization name |
SJTU
|
| Street address |
320 Yueyang Road
|
| City |
Shanghai |
| ZIP/Postal code |
200031 |
| Country |
China |
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| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA1020064 |
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