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| Status |
Public on Mar 31, 2011 |
| Title |
Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by genome tiling array
Methylation profiling by genome tiling array
|
| Summary |
Analysis of cross talk of epigenetic marks in HBEC by using tilling arrays chr19. In Human Bronchial epithelia cells (HBEC), H3K9me3, H4K20me3, H3K4me3, H3K27me3, H3K36me3 and DNA methylation were profiled. In these cells, DNA methylation status was analyzed by MIRA and UnmethylCollector (UMC).
Study of epigenetic changes in HCT116 DNMT1-/- and DNMT3b -/- (HCT116-DKO) in comparison to intact HCT116. In HCT116 and HCT116-DKO, H3K9me3, H3K36me3 and DNA methylation were profiled. In these cells, DNA methylation status was analyzed by MIRA.
Analysis of epigenetic changes caused by siRNA for SED2 transcript in HBEC. In HBEC and SETD2 siRNA HBEC, H3K36me3 and DNA methylation were profiled. In these cells, DNA methylation status was analyzed by MIRA.
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| |
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| Overall design |
Comapre DNA methylation and other histone modification marks
|
| |
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| Contributor(s) |
Hahn MA, Wu X, Li AX, Hahn T, Pfeifer GP |
| Citation(s) |
21526191 |
| |
| Submission date |
Dec 14, 2010 |
| Last update date |
Mar 23, 2012 |
| Contact name |
Xiwei Wu |
| E-mail(s) |
xwu@coh.org
|
| Organization name |
City of Hope National Medical Center
|
| Department |
Computational and Quantitative Medicine
|
| Street address |
1500 E. Duarte Rd.
|
| City |
Duarte |
| State/province |
CA |
| ZIP/Postal code |
91010 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11313 |
NImbleGen Chromosome 19 Tiling Array |
|
| Samples (17)
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| This SubSeries is part of SuperSeries: |
| GSE26020 |
Crosstalk between gene body DNA methylation, H3K9me3 and H3K36me3 chromatin marks and transcription |
|
| Relations |
| BioProject |
PRJNA142517 |
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